1 case of intracranial isolated fibrous tumor

1Case informationfemale, 70 years old, admitted to hospital for six months due to inability to lower right limbAdmitted to the hospital physical examination: clear mind, right lower limb muscle strength IV level, the rest of the limb muscle strength Vclass, double-sided papsmearnegative negativeHead MRI shows the right side of the brain side see soft tissue lump shadow, see within or low T1, slightly higher and low T2 signal shadow, border clearing, enhanced scanning significantly strengthened, consider meningiomaDuring the operation, the tumor is seen attached to the epidural, the tumor blood supply is rich, the texture is soft, gray whitepostoperative pathology examination showed: interlocutory tumors, cell-based, with cell short cother-shaped, less interstitial, higher value-added index, active growth; (-), CgA (-), ERG (-), Syn (-), EMA (-), GFAP (-), S-100 (-), Calponin (-), CD34 (-), P63 (-), CD99 (-), consider isolated fibrosis tumor (soaryan fibrous tumor, SFT)2Discussion
SFT is a rare shotriatal cell tumor of the origin of interlocutory tissue, first reported by Paul et alin 1931, in the pleural cavityIt was subsequently found that SFT could also occur in other parts of the body, at any age, withno significant gender differencesIt is very rare to have an intracranial isolated fibrous tumor (intracranial SFT, ISFT) that originated in the cranial bodySFT originated from the primitive interstitial stem cells, and the lens has a variety of forms, but still has the following characteristics: mainly composed of collagen fiber and fibroblast-like tumorsTypical SFT is mainly distributed alternately by cell enrichment and cell sparseness In a few cases there is also mucus-like or transparent denaturation Its collagen fiber is relatively rich, even glass-like change, tumor cells are gentler, tumor proliferation of blood vessels, more fissure, antler-shaped or branched The degree of cell enrichment varies greatly in each region, and the cell-rich are easily misdiagnosed as fibroids and malignant neurosaromas ISFT MRI examination showed isolated round or oval lumps, T1WI is an equal signal, T2WI is an equal, low promiscuous signal, DWI is a low signal; Studies have shown that the accuracy rate of preoperative diagnosis of SFT is almost zero outside the pleural body ISFT is often found when symptoms of oppression are evident The case in this paper only shows the weakness of the right lower extremity, no other associated symptoms isFT identification diagnosis: (1) fibroblast-type meningioma, visible small island-like meningioma cells, collagen fibroblasts with no or small amounts, tumor cells CD34 negative or stove-positive (2) neuroblastoma, shuttle cell nucleus is often fence-like arrangement, tumor cells without erythema-dyed collagen fiber, visible hyperplasia glass-like thick walled hemangio; tumor cells S-100 positive, Leu-7 and GFAP can also be positive (3) Low-level malignant fibroid, tumor cells with "fish bone-like" or "human" character arrangement characteristics, immune histification showvitin positive, SMA partial positive, CD34 and Bcl-2 negative most SFts are benign, but 10% to 15% are still invasive For "small" SFTs found during physical examination, surgical intervention should be promptly followed once it is found that its growth is found ISFT in the microscope downthetumor full cut is currently the best treatment, postoperative prognosis is good, but need long-term follow-up in short, ISFT is very rare, preoperative lying easily, need to rely on pathology confirmation Clinical and pathologists need to be vigilant and raise awareness of the tumor in order to reduce misdiagnosis