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The treatment of NTM lung disease should be considered in combination with pathogenic microorganisms, drug sensitivity, imaging findings and disease severity.
Generally speaking, more than three drugs should be used at the same time to reduce induced drug resistance.
After turning negative, she continued to use medication for 12 months.
Therefore, the side effects of treatment will be more frequent, which affects compliance and treatment effect.
The latest guidelines recommend that for patients with mild/moderate non-cavitary NTM lung disease and slower disease progression, it is more recommended to receive treatment 3 times a week instead of daily, and patients will be better tolerated.
Please refer to the following two tables for the sensitivity of commonly used therapeutic drugs to different strains and the drug recommendations of the main strains of NTM lung disease: Table 1 Sensitivity of commonly used drugs to different NTM strains (click to view the larger image) Note: +++ is Strong antibacterial activity; ++ for general antibacterial activity; + for weaker antibacterial activity;-for drug resistance Table 2 Recommendations for medication of the main strains of NTM lung disease (click to view larger image) References: 1.
Gill LI , Dominic C, Tiberi S.
Atypical mycobacterial infections-management and when to treat.
Curr Opin Pulm Med.
2021 May 1;27(3):216-223.
2.
Chinese Medical Association Tuberculosis Branch.
Nontuberculous Mycobacterial Diseases Guidelines for diagnosis and treatment (2020 edition)[J].
Chinese Journal of Tuberculosis and Respiratory Medicine, 2020, 43(11):918-946.
Generally speaking, more than three drugs should be used at the same time to reduce induced drug resistance.
After turning negative, she continued to use medication for 12 months.
Therefore, the side effects of treatment will be more frequent, which affects compliance and treatment effect.
The latest guidelines recommend that for patients with mild/moderate non-cavitary NTM lung disease and slower disease progression, it is more recommended to receive treatment 3 times a week instead of daily, and patients will be better tolerated.
Please refer to the following two tables for the sensitivity of commonly used therapeutic drugs to different strains and the drug recommendations of the main strains of NTM lung disease: Table 1 Sensitivity of commonly used drugs to different NTM strains (click to view the larger image) Note: +++ is Strong antibacterial activity; ++ for general antibacterial activity; + for weaker antibacterial activity;-for drug resistance Table 2 Recommendations for medication of the main strains of NTM lung disease (click to view larger image) References: 1.
Gill LI , Dominic C, Tiberi S.
Atypical mycobacterial infections-management and when to treat.
Curr Opin Pulm Med.
2021 May 1;27(3):216-223.
2.
Chinese Medical Association Tuberculosis Branch.
Nontuberculous Mycobacterial Diseases Guidelines for diagnosis and treatment (2020 edition)[J].
Chinese Journal of Tuberculosis and Respiratory Medicine, 2020, 43(11):918-946.