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    Home > Biochemistry News > Biotechnology News > 2022-04-19 Cell Reports The research group of Chen Yuxing and Zhou Congzhao revealed the molecular mechanism of cytoplasmic membrane sphingomyelin-assisted intracellular cholesterol efflux

    2022-04-19 Cell Reports The research group of Chen Yuxing and Zhou Congzhao revealed the molecular mechanism of cytoplasmic membrane sphingomyelin-assisted intracellular cholesterol efflux

    • Last Update: 2022-05-20
    • Source: Internet
    • Author: User
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    The research group of Prof.



    Cholesterol, as a major component of the plasma membrane of mammalian cells , plays a key role in maintaining membrane fluidity and stability and in the synthesis of bile acids, steroid hormones, and vitamin D



     Figure 1 Three-dimensional structure of ABCG1 and its molecular mechanism of cholesterol transport


    This paper reports a three-dimensional structure of ABCG1 with an open-to-intracellular conformation



    Professor Chen Yuxing, Professor Zhou Congzhao and Hou Wentao are the co-corresponding authors of the paper, and Dr.



    Original link: https:// class="cjk" >



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