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    Home > Biochemistry News > Biotechnology News > 3D printed human heart tissue that can work normally

    3D printed human heart tissue that can work normally

    • Last Update: 2020-06-08
    • Source: Internet
    • Author: User
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    All human organs, including the heart, are built on a biological stent called extracellular matrix (ECM), which scientists have tried to print in the past, but has been constrained by poor tissue reduction and finenesscollagen is present in all tissues of the human body and is an ideal 3D-printed biomaterialBut it starts out as liquid and, in the process of trying 3D printing, turns into jelly-like glueresearchers developed FRESH technology to prevent its deformationFRESH allows collagen to be superimposed layer by layer in the gel support tank, which is then melted by heating from room temperature to body temperature to get a good structureThese structures can be as fine as 20 microns and can be embedded in living cells and capillariesWith this approach, human heart components can be designed to print on a variety of scales, from capillaries to the entire organthe study found that the heart of FRESH 3D bioprinting accurately reproduces patient-specific anatomical structures determined by microcomputed tomographyThe heart ventricle of printed human heart muscle cells showed simultaneous contraction, directional motion potential profane propagation, and wall thickening of up to 14% during contraction peaksresearchers also say the structures created by the new technology can "greatly improve cell vitality" and promote the production of new blood vesselsIn the long run, the technology could be used to print hearts or other organs in the future -- millions of people around the world need heart transplants, of course, there are many challenges to achieving this goal, including the billions of cells needed to generate large tissues for bioprinting, and following regulatory procedures to test animals and ultimately in humans.
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