4D print blocker disappears after repairing heart "loophole"

Statistics show that congenital heart disease accounts for about 28% of all common congenital abnormal diseases in clinical practiceThere are more than 100,000 new cases of congenital heart disease in newborns in China each yearAmong them, room interval defect is a typical pre-heart diseaseSince its invention in the 1970s, the heart blocker has been widely used as an interventional treatment for pre-heart diseaseAt present, the heart blockers on the market are mainly woven from the shape memory nickel-titanium alloy wire, although these blockers can provide effective sealing, but there are non-degradable, metal ion sepsis, conduction block, thrombosis, hemolytic, nickel allergy, corrosion or poisoning and other complicationsCanblocker become a temporary "bridge"? That is, after implanting the heart, the surrounding tissue gathers together in the blocker, the growth is completed to endothelialization, and the role of the blocker is completed, that is, gradually self-degradation and absorption by the bodyWith the support of several national natural funds, the Cold Jinsong team worked closely with Harbin Medical University Cardiology to combine programmable shape memory polymers with 4D printing technology to design and prepare personalized, biodegradable shape memory polymer blockersexperts evaluate that 4D printing personalized biodegradable shape memory polymer blocker, is expected to successfully solve the metal blocker non-degradable, allergy, corrosion, poor biocompatibility and other issues, with a very broad application prospects, is expected to become a potential replacement device for metal blockers.