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Two important research findings on human genetics were published online Thursday in the British journal Nature Genetics: A team of European scientists conducted genetic analysis of more than 250,000 individuals and 500,000 individuals, respectively, to identify hundreds of new genetic sites associated with intelligence and neuroticism.
results greatly broaden human understanding of cognitive function.
intelligence genetics are complex, and scientists have thought that perhaps no gene can have a huge impact.
but genetic quality is the biological premise of intellectual development, we must gradually uncover the genetic sites related to intelligence, so that we can further understand the neurobiological basis of intelligence at the molecular level.
and depression disorder, a mental illness, is mainly a clinical feature of significant and persistent low mood, also known as depression.
so far, the cause of depression is not very clear, but it is certain that biological factors are involved in the onset of depression - this factor mainly involves genetic, neuro-biochemical and so on. In one of the
study, Danielle Possuman, a scientist at the Free University of Amsterdam in the Netherlands, and colleagues first analyzed genetic and intelligence measurements from more than 250,000 individuals and found 190 new genetic sites and 1,016 specific genes associated with intelligence -- 939 of which were new. Based on the analysis, the
team suggested that increased intelligence may prevent Alzheimer's disease and ADHD.
they also identified genetic pathways associated with nervous system development and synaptic structure.
in another study, the team focused on neuroticism, an important risk factor for depression and schizophrenia.
they identified more than 500 genes associated with neuroticism by analyzing nearly half a million individuals.
team described two different neurotic sub-groups, one related to depression and the other with distress.
combined, these two studies provide new insights into the neurobiological and genetic basis of understanding and cognition.
researchers believe the latest data could help future research on neuropsychiatric disorders.
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