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    Home > Active Ingredient News > Endocrine System > A 32-year-old boy with coronary heart disease, acute pancreatitis, and diabetes came to the door together. The reasons behind it are worthy of alert!

    A 32-year-old boy with coronary heart disease, acute pancreatitis, and diabetes came to the door together. The reasons behind it are worthy of alert!

    • Last Update: 2021-06-18
    • Source: Internet
    • Author: User
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    *It is only for medical professionals to read and refer to.
    I hope this case can be a lesson for many young people with similar living habits! The 38-year-old Da Liu is a northeastern man, 1.
    74m tall and 90kg in weight.
    He looks very strong, but such a strong man has frequent physical problems
    .

    8 years ago, he was 30 years old
    .

    Liu had a sudden abdominal pain.
    He went to the hospital for acute pancreatitis and was hospitalized quickly
    .

    Acute pancreatitis is a severe acute abdomen with a high mortality rate.
    Fortunately, he went to the doctor promptly and no serious consequences occurred
    .

    Further examination during hospitalization also found that blood lipids were extremely high, and blood sugar was also high
    .

    However, he felt that he was still young and had good health.
    He didn't take high blood fat and high blood sugar indicators seriously, and he didn't take any medication after he was discharged from the hospital
    .

    7 years ago, he was 31 years old
    .

    Da Liu had a recurrence of acute pancreatitis, and he was hospitalized again.
    During the hospitalization, he was still found to have high blood lipids and high blood sugar.
    After he was discharged from the hospital, he had not taken it seriously and had no follow-up treatment
    .

    6 years ago, he was 32 years old
    .

    Liu had a sudden chest pain and went to the doctor urgently.
    This time it was not acute pancreatitis, but acute myocardial infarction, which was more serious than acute pancreatitis.
    Fortunately, he went to the doctor in time.
    Two stents were placed on the heart, which saved his life
    .

    This time the hospitalization check found that the fasting blood glucose was more than 20mmol/L.
    The cardiologist warned him that if he does not control his blood sugar and blood lipids, not only other blood vessels will be blocked, but the stent will also be blocked again
    .

    This time, he realized that he was scared.
    After he was discharged from the hospital, he began to treat diabetes, and he continued to use insulin
    .

    But the medication is not regular, and the blood sugar is not controlled normally
    .

    2 years ago, he was 36 years old
    .

    Liu found proteinuria on a routine physical examination.
    He didn't care about it at first.
    He didn't go to the nephrology department for medical treatment, and he didn't get treatment for proteinuria
    .

    I reviewed the increase in urine protein some time ago, and consulted me from the Internet, and started to add empagliflozin treatment, and the urine protein decreased.
    Later, I was not relieved, so I came to me directly from other places
    .

    After admission, blood pressure was 160/100mmHg, urine protein was 0.
    47g/d, fasting blood glucose was 11.
    5mmol/L, glycosylated hemoglobin was 8.
    9%, triglyceride was 14.
    8mmol/L, and blood uric acid was 575μmol/L, as shown in Figure 1
    .

    Figure 1 Examination results after admission.
    From these examination results, you will find that his blood sugar and blood lipids are still very high, blood pressure and blood uric acid are also high.
    It is speculated that he has neither regular, coordinated treatment nor changed his unhealthy life>
    .

    With such high triglycerides, acute pancreatitis is still inevitable.
    With such high blood sugar and blood pressure, myocardial infarction may occur again.
    If things continue like this, urine protein will become higher and higher.
    I really can’t imagine what he will do in 10 years.
    So, at that time, he was just 48 years old and just entering middle age
    .

    People can't help asking, doesn't coronary heart disease occur only in middle age, why did he develop coronary heart disease and acute myocardial infarction at a young age? Why does he have repeated acute pancreatitis? Is acute pancreatitis related to diabetes? 01 How does coronary heart disease happen? Coronary heart disease does not happen arbitrarily, there must be a cause and an effect, and an effect must have a cause
    .

    The arteries that supply blood to the heart are called coronary arteries and are divided into three branches
    .

    Coronary heart disease refers to the occurrence of atherosclerosis in the coronary arteries, which narrows or occludes the vascular lumen, leading to myocardial ischemia, hypoxia or necrosis.
    In severe cases, the heartbeat stops
    .

    Coronary heart disease is a common and frequently-occurring disease of middle-aged and elderly people.
    In recent years, it has been younger and has become one of the main diseases that threaten human life and health
    .

    Hyperlipidemia, hypertension, diabetes, and smoking are the four major risk factors for coronary heart disease.
    In addition, obesity, staying up late, and long-term heavy drinking are also risk factors for coronary heart disease
    .

    The occurrence of coronary heart disease is definitely the result of the long-term effect of one or several of the above risk factors
    .

    Generally speaking, some people start smoking and drinking at the age of 20 or 30, and become obese at the age of 30 or 40, and develop hypertension, diabetes, hyperlipidemia, etc.
    These risk factors are not controlled after they appear, and it takes about 10 years.
    Coronary heart disease will occur, so most of them appear in middle age
    .

    If smoking and drinking are fierce, and the "three highs" are severe, the occurrence of coronary heart disease will be advanced.
    There are not a few people who are in their 30s like this Northeast man who do stents
    .

    He is relatively fat.
    He only discovered diabetes and hyperlipidemia when he was hospitalized for the first time at the age of 30.
    It is speculated that diabetes and hyperlipidemia appeared earlier.
    He just didn't check and found it
    .

    With such a high index, he has neither lost weight, nor changed his unhealthy life>
    .
    It is not difficult to understand how to get a heart stent at the age of 32 .

    Let's talk about acute pancreatitis
    .

        02 Why did he repeatedly develop acute pancreatitis? Acute pancreatitis refers to the self-digestion, edema, hemorrhage, and even necrosis of pancreatic tissue caused by various causes
    .

    Twenty years ago, the mortality rate of acute pancreatitis was very high, reaching 15.
    8%
    .

    At present, due to the improvement of the emergency system and the improvement of treatment technology, the mortality rate of acute pancreatitis has dropped to about 5%
    .

    Cholelithiasis and biliary tract diseases are the main causes of acute pancreatitis, accounting for about 50%, followed by drinking
    .

    In recent years, with the increase in hyperlipidemia, especially hypertriglyceridemia, the proportion of pancreatitis caused by high triglycerides is 25.
    6%, which has become the third cause of pancreatitis, second only to bile source.
    Pancreatitis and alcoholic pancreatitis
    .

    Blood lipids mainly include triglycerides and cholesterol, and cholesterol is divided into high-density cholesterol (high-density lipoprotein) and low-density cholesterol (low-density lipoprotein)
    .

    The biggest harm of low-density lipoprotein is to cause atherosclerosis such as coronary heart disease and cerebral infarction, and the biggest harm of high triglycerides is acute pancreas
    .

    Studies have found that when triglycerides exceed 11.
    3 mmol/L, the incidence of pancreatitis will increase by 5 to 10 times, and when it exceeds 22.
    6 mmol/L, the incidence will increase by 10 to 40 times
    .

    High low-density lipoprotein has little to do with diet, but high triglycerides are directly related to diet and drinking.
    Animal offal, shellfish, oily foods, sweets, etc.
    are the main foods that raise triglycerides, and a small amount Drinking alcohol can also cause significant increases in triglyceride levels
    .

    Seeing this knowledge, everyone guessed the reason for this patient's high blood lipids, and it was found that the high blood lipids did not change his life>
    .

        03 What is the relationship between pancreatitis and diabetes? One of the main functions of the pancreas is to secrete insulin, and the main function of insulin is to regulate blood sugar
    .

    Pancreatitis and diabetes are a pair of "enemies" that are hard to give up
    .

    Diabetes and pancreatitis have similar causes and common pathogenesis, in addition, the two promote and influence each other
    .

    First of all, diabetes can cause lipid metabolism disorders, especially hypertriglyceridemia, and hypertriglyceridemia is one of the main risk factors for pancreatitis
    .

    Secondly, chronic pancreatitis leads to massive destruction of islet cells, insufficient insulin secretion, and insufficient insulin secretion to cause diabetes
    .

    Even more frightening is that when diabetes encounters pancreatitis, when the two coexist, it will bring greater harm to health: diabetic ketoacidosis, diabetic hypertonic state, hypoglycemia, coronary heart disease, diabetic nephropathy and other diabetes Acute and chronic complications
    .

    This patient's diabetic nephropathy is the result of long-term uncontrolled or poorly controlled blood pressure and blood sugar, and pancreatitis of diabetes
    .

    When he was first admitted to the hospital, because his blood sugar was too high, we did not dare to do a glucose tolerance test.
    After the blood sugar was sometimes controlled, we did a glucose tolerance test for him to understand his pancreatic function after 2 acute pancreatitis
    .

    Fortunately, his basal insulin secretion is not affected, but insulin secretion during meals has been significantly impaired, as shown in Figure 2
    .

    Figure 2 Pancreatic function test results.
    In short, unhealthy life>
    .

    However, it is not too late to start regular treatment.
    Improve life>
    .

    From this patient’s life>
    .

    It is hoped that this case can be a lesson for many young people with similar living habits
    .

    Source of this articleResponsible Editor of Nephrology PopularizationBoom Boom Copyright Statement
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