A high-resolution complete 3D atlas of the mouse brain was released

After three years of intensive data collection and careful mapping, the work of the mapters was completed.
In a paper published May 7 in Cell, scientists at the Allen Institute for Brain Science described the feat as the third edition of the Allen Mouse Brain General Coordinate Framework (CCFv3), a complete, high-resolution 3D atlas of the brains of mice.
are widely used in biomedical research, and their brains contain about 100 million cells, each spread over hundreds of different regions.
, people used to define different areas of the brain with their eyes, " he says. As more and more data emerges, manual management is difficult to meet, just as we have a reference genome sequence, and people need a reference anatomy. Lydia Ng of the Allen Institute for Brain Science said.
the 2016 version of CCFv3, which mapped the entire cortical layer of the outer outerm of the mouse brain.
to create the atlas, the researchers divided the brain into tiny virtual 3D blocks and assigned a unique coordinate to each block.
researchers say you can think of it as mobile GPS in neuroscience.
history, brain atlases have been drawn in 2D, looking at the brains from different depths and arranging them.
Steinmetz, an assistant professor at the University of Washington, said they used CCFv3 to analyze data and found that the brain was more involved in visual selection than they had previously realized. "There has to be a big picture, and CCFv3 can help us see all the results together." He said.
researchers say future atlases may rely on machine learning or other forms of automation, rather than the laborive manual management of current versions.
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