A low-salt diet increases the risk of cardiovascular disease?!

traditional concept, a high-salt diet is an important factor in high blood pressure. However, a study in the Lancet, an internationally renowned medical journal, showed that for people who already have high blood pressure, a low-salt diet actually increases the risk of high blood pressure! What the hell is going on here?low salt or high salt? Perhaps it's possible Professor
Andrew Mente
of
McMaster
University, a leading Canadian medical institution, is an expert in clinical epidemiology and biostatists, and some of the literature he read notes that salt consumption and cardiovascular risk and mortality are
U
in a way that means high and low salt intake increases the risk
Mente
convened a team to conduct a big data analysis of
135 million people in
49,
countries in
4,
related large
-scale studies, to count daily urinary sodium and cardiovascular disease and deaths, to analyze the relationship between sodium urine and cardiovascular risk by statistical means, and to group whether or not they had previously suffered from hypertension
.results are indeed the same as in the literature, the cardiovascular risk ratio is
U
-type relationship with sodium urine:From the overall sample, when sodium urine reaches about
5000mg/d
, the risk ratio is the lowest, too high and too low to increase the risk of cardiovascular eventsfor the hypertension group, the correlation between sodium urine and cardiovascular events is the same as in the population. For non-hypertension groups, however, the risk of cardiovascular events from a low-sodium diet was much higher than that associated with a high-sodium diet





The average upward trend of
SBP
and
DBP
was different for each
1g
sodium, hypertension and non-hypertension groups (
SBP
:
2.08 vs 1.02 mmHg
;
DBP
:
0.72 vs 0.52 mmHg
,
p
<
0.0001
) theteam found that only
10 percent of people on a high-salt diet (sodium consumption>
6g/d
) had a risk of cardiovascular events
, compared with
24 percent of people with high blood pressure
. This shows that the increased risk of cardiovascular events caused by a high-salt diet is more prominent in people with high blood pressure. For non-hypertensive people on a low-salt diet (sodium consumption <
3g/d
), the risk of cardiovascular disease increased by
26%
(
p s0.0009
). This leads to the conclusion that a low-salt diet increases the risk of cardiovascular disease in non-hypertensive populations, and suggests that ways to reduce sodium intake are best directed at people with high sodium intake (approximately
11%
).and controversy coexist
once a conclusion that subverts traditional ideas comes out, it will be controversial. Similarly, not everyone bought the results of the study. Dr.
Antman
, former president of the American Heart Association (
AHA
), said measuring sodium urine to estimate sodium intake over a period of time was a fatal flaw in the study.And Dr
O
'
Brien
of the University of Dublin, writing in an op-ed in The Lancet, says that when a traditional dogch is challenged, we should look at it as "scientifically possible" and that it is wrong for 10th party to "kill with a stick".the conclusion that "low salt increases the risk of cardiovascular disease" has been done, and has even been withdrawn on one occasion because "the results should not change people's minds and practices." But the rebuttal to this withdrawal has been repeated and repeated.
led by
Mente, may be the most convincing so far.there is no doubt that these provocative conclusions in the study will certainly be challenged, and the method of estimating
24,
hours of sodium excretion by urinary sodium is controversial. However, it is thought that the benefits of low salt intake strategies in all populations outweigh any possible harmful effects. However, without an accurate definition of the latter risk, this approach is inherently flawed.large
-
-looking observational study by the Mene research team did provide supporting evidence, but did not give cause-and-effect. It is encouraging to note that a randomized controlled pilot study to look at this issue has been initiated (
STICK
study).
OBrien
commented, "Because sodium ions involve many physiological processes, it is not surprising that low salt intake strategies in all populations benefit some people and disadvantage some." ”