A molecular thermometer for thermal regulation of turtle embryo behavior

Suitable body temperature is the prerequisite and guarantee for animals to maintain basic life activities such as feeding, breathing, metabolism, development and reproduction

May 19, 2021, Institute of Zoology, Chinese Academy of Sciences researcher Du Weiguo joint team LAI Ren Chinese Academy of Sciences Kunming Institute of Zoology researcher team and the Northeast Forestry University, Professor Yang Shilong team in Current Biology published online entitled "Molecular sensors for temperature detection during behavioral thermoregulation in turtle embryos" research paper

The researchers measured the temperature threshold of primary sensory neurons in the tortoise embryo and its dorsal root ganglion (DRG), and found two types of heat-sensitive neurons consistent with the embryo’s thermal preference temperature threshold, indicating that there are at least two primary sensory neurons.

The researchers further found that capsaicin and 4-aminobenzidine hydrochloride (4-A) are specific activators of tortoise TRPA1, TCS5861528 (TCS) is a specific inhibitor; capsaicin and capsaicin are specific for TRPV1 Activator and inhibitor

Researcher Du Weiguo from Institute of Zoology, Chinese Academy of Sciences, Researcher Lai Ren from Kunming Institute of Zoology, Chinese Academy of Sciences, and Professor Yang Shilong from Northeast Forestry University are the co-corresponding authors of the paper, Ye Yinzi, postdoctoral fellow from Institute of Zoology, Chinese Academy of Sciences, Dr.

Figure 1 Chemical intervention and tortoise embryo movement

Article link: https://doi.

1 Angilletta, MJ Thermal adaptation: A theoretical and empiricial synthesis .

2 Zhao, B.

　　3 Du, WG, Zhao, B.

　　4 Ye, YZ et al.