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    Home > Biochemistry News > Microbiology News > A Multianalyte Method for the Quantification of Current-Use Pesticides in Human Serum or Plasma Using Isotope Dilution Gas Chromatography-High-Resolution Mass Spectrometry

    A Multianalyte Method for the Quantification of Current-Use Pesticides in Human Serum or Plasma Using Isotope Dilution Gas Chromatography-High-Resolution Mass Spectrometry

    • Last Update: 2021-01-30
    • Source: Internet
    • Author: User
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    We propose a sensitive and accurate analytical method for quantifying 29 current-use pesticides in human serum or plasma. These pesticides include organophosphates, carbamates, chloroacetanilides, and synthetic pyrethroids, pesticides used in both agricultural and residential settings. Our method employs simple solid-phase extraction followed by highly selective analysis using isotope dilution gas chromatography-high-resolution mass spectrometry. The method is very accurate, has limits of detection (LODs) in the low picogram/gram range, and has coefficients of variation that are typically less than 20% at the low picogram/gram end of the method linear range.
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