A new concept of Hox gene expression - segmented collinearity.

Nature Ecology and Evolution, a sub-issue of Nature, recently published online in Article the research paper "Scallop genome institute insights into evolution of bilaterian karyotype and development", which was co-authored by liu Baozhong of the Institute of Oceanographic Research of the Chinese Academy of Sciences.
the study was conducted by China Ocean University, the Institute of Oceans of the Chinese Academy of Sciences, Bergen University in Norway, Rutgers University in the United States and other organizations. The
team analyzed the entire genome sequence of the important biscep shrimp scallops and found that the scallop genome changed slowly over a period of more than 300 million years, with the structure of all 19 pairs of chromosomes maintaining striking consistency with the 17 pairs of chromosomes predicted by the common ancestor of most existing animals, a conservatism far greater than that of other animals with known genomic information.
analysis of the Hox gene, the researchers came up with a new concept for Hox gene expression -- segmented collinearity (subcluster temporal co-linearity, STC).
, Liu Baozhong's team systematically analyzed the dynamic expression laws of all 11 Hox genes in embryos and larvae, and the results fully supported the STC hypothesis, which provided the paper with key experimental biological evidence.
a: Composition of the shrimp scallop Hox gene; b: clustering analysis of the Hox gene between scallops and other coronary animals; c: transcriptional group analysis showed that the Hox gene was segmented and colinear in expression time; and d: four leding Hox genes were spatially colinearly expressed in scallop embryos.
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