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Against the backdrop of the COVID-19 pandemic raging around the world, amazing progress has been made in the field of vaccine research and development, and there are more and more different types of vaccines developed based on different principles
The research team injected the uniquely designed spherical nucleic acid Covid-19 vaccine into mice subcutaneously to elicit an immune response to the SARS-CoV-2 spike protein, and then monitored antibody production for several weeks after injection
Not only that, the research team also sent their vaccine to Argonne National Laboratory (ANL) in the United States for testing of new coronavirus in live animals.
Professor Chad Mirkinsaid the study confirmed the importance of vaccine structure, which can have a profound impact on the efficacy of vaccines
Against the backdrop of the COVID-19 pandemic raging around the world, amazing progress has been made in the field of vaccine research and development, and there are more and more different types of vaccines developed based on different principles
Structural pattern diagram of the spherical nucleic acid new crown vaccine The research team injected this uniquely designed spherical nucleic acid new crown vaccine into mice subcutaneously to induce an immune response to the new coronavirus spike protein, and then monitored the production of antibodies within a few weeks after injection.
The spherical nucleic acid new crown vaccine induces the production of higher titers of neutralizing antibodies.
100% of the mice in the SNA vaccine protected experimental group The SNA vaccine protected 100 % of the mice in the experimental group.
Professor Chad Mirkin Chad Mirkin Prevention of Emerging Infectious Diseases Prevention of Emerging Infectious Diseases The COVID-19 pandemic has caused hundreds of millions of infections and millions of deaths worldwide, and has had a profound impact on human society, which also highlights emerging infectious diseases terrifying .
Therefore, how to effectively prevent emerging infectious diseases has become a difficult problem that human beings must face .
Today, this research provides an answer to that question to some extent .
Dr Max Distler, co-first author of the study , said that while these experimental results were impressive, the team's goal was not to compete with existing Covid-19 vaccines, but to develop a new vaccine for the next infectious disease that requires a highly structured vaccine.
be prepared .
The spherical nucleic acid platform could even be used to treat complex diseases like AIDS .
Professor Max Distler Chad Mirkin said that the modularity of the spherical nucleic acid vaccine research and development platform means that once a new infectious disease occurs, it may only be necessary to replace the antigen or adjuvant to quickly respond to future viruses .
Therefore, spherical nucleic acid is not only a drug or a vaccine, but a research and development platform for various diseases and infectious diseases, which can help humans overcome intractable diseases such as cancer and emerging infectious diseases .
Chad Mirkin 's paper link: https:// https://stm.
sciencemag.
org/content/13/584/eabb3945 Leave a comment here
The research team injected the uniquely designed spherical nucleic acid Covid-19 vaccine into mice subcutaneously to elicit an immune response to the SARS-CoV-2 spike protein, and then monitored antibody production for several weeks after injection
Not only that, the research team also sent their vaccine to Argonne National Laboratory (ANL) in the United States for testing of new coronavirus in live animals.
Professor Chad Mirkinsaid the study confirmed the importance of vaccine structure, which can have a profound impact on the efficacy of vaccines
Against the backdrop of the COVID-19 pandemic raging around the world, amazing progress has been made in the field of vaccine research and development, and there are more and more different types of vaccines developed based on different principles
Structural pattern diagram of the spherical nucleic acid new crown vaccine The research team injected this uniquely designed spherical nucleic acid new crown vaccine into mice subcutaneously to induce an immune response to the new coronavirus spike protein, and then monitored the production of antibodies within a few weeks after injection.
The spherical nucleic acid new crown vaccine induces the production of higher titers of neutralizing antibodies.
100% of the mice in the SNA vaccine protected experimental group The SNA vaccine protected 100 % of the mice in the experimental group.
Professor Chad Mirkin Chad Mirkin Prevention of Emerging Infectious Diseases Prevention of Emerging Infectious Diseases The COVID-19 pandemic has caused hundreds of millions of infections and millions of deaths worldwide, and has had a profound impact on human society, which also highlights emerging infectious diseases terrifying .
Therefore, how to effectively prevent emerging infectious diseases has become a difficult problem that human beings must face .
Today, this research provides an answer to that question to some extent .
Dr Max Distler, co-first author of the study , said that while these experimental results were impressive, the team's goal was not to compete with existing Covid-19 vaccines, but to develop a new vaccine for the next infectious disease that requires a highly structured vaccine.
be prepared .
The spherical nucleic acid platform could even be used to treat complex diseases like AIDS .
Professor Max Distler Chad Mirkin said that the modularity of the spherical nucleic acid vaccine research and development platform means that once a new infectious disease occurs, it may only be necessary to replace the antigen or adjuvant to quickly respond to future viruses .
Therefore, spherical nucleic acid is not only a drug or a vaccine, but a research and development platform for various diseases and infectious diseases, which can help humans overcome intractable diseases such as cancer and emerging infectious diseases .
Chad Mirkin 's paper link: https:// https://stm.
sciencemag.
org/content/13/584/eabb3945 Leave a comment here
