echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Biochemistry News > Biotechnology News > A new PARP-like enzyme discovered in mitochondria

    A new PARP-like enzyme discovered in mitochondria

    • Last Update: 2022-03-04
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    To characterize the enzymatic activity of NEURL4, a team led by first and co-corresponding author Maria Dafne Cardamone, Ph.


    According to the researchers, this approach allowed them to identify a number of mitochondrial proteins as targets of NEURL4, including mitochondrial LIG3, a protein involved in the repair of damaged mitochondrial DNA, and confirmed that the activity of NEURL4 is to maintain mitochondrial DNA (mtDNA) required for completeness


    While the study does not have any immediate implications for clinical treatment, the team said it represents an important step in understanding how cells maintain homeostasis and respond to oxidative stress


    The researchers believe that future studies of how NEURL4-mediated modification of specific mitochondrial proteins affects mitochondrial function may lead to the identification of new regulatory strategies for therapeutic purposes



    Maria Dafne Cardamone, Yuan Gao, Julian Kwan, Vanessa Hayashi, Megan Sheeran, Junxiang Xu, Justin English, Joseph Orofino, Andrew Emili, Valentina Perissi.





    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Related Articles

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.