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On September 26th, the news came from Nanjing University of Technology that Huang Wei, academician of the Chinese Academy of Sciences, Professor An Zhongfu's team and Professor Chen Hongmin of Xiamen University cooperated with the research group of Professor Chen Hongmin of Xiamen University to achieve high-efficiency photodynamic therapy at low X-ray doses using pure organic phosphorescence scintillator materials, showing the great application potential
of such materials in deep tumor treatment.
In view of this scientific problem, the research team achieved radiosensitivity by introducing heavy atoms, using heavy atoms and nitrogen, oxygen and other elements containing solitary pairs of electrons to promote the interlineage leap between the monomeric state and the trilinear state, thereby promoting the generation of trilinear excitons, preparing a photosensitizer that can directly use X-rays, and combining the scintillator and the photosensitizer into one
.
"This is different from the traditional X-ray excitation scintillator as an energy medium, relying on the energy transfer between the scintillator and the photosensitizer, our pure organic phosphorescent scintillator material can directly absorb X-rays, but also as a photosensitizer, combining the two functions into one, improving the energy conversion efficiency of X-rays, thereby improving the effect of
X-ray photodynamic therapy.
Pure organophosphorescence scintillators are materials that the team has been working on for a long time
.