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    Home > Active Ingredient News > Endocrine System > A study of over 180,000 people found that birth control pills may reduce the risk of type 2 diabetes in women with polycystic ovary syndrome

    A study of over 180,000 people found that birth control pills may reduce the risk of type 2 diabetes in women with polycystic ovary syndrome

    • Last Update: 2021-11-02
    • Source: Internet
    • Author: User
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    Polycystic ovary syndrome affects 10 percent of women in the world, in the long run also associated with other diseases, such as endometrial cancer, heart blood vessel disease-related and non-alcoholic fatty liver (NAFLD)
    .

    Heart blood vessels

    Symptoms of polycystic ovary syndrome include irregular or amenorrhea, which can lead to fertility problems.
    Many people suffer from "hirsutism", hair loss, and oily skin or acne.
    These symptoms are caused by high levels of androgens in the blood
    .

    Women with polycystic ovary syndrome also often struggle with weight gain.
    The cells in their bodies often respond poorly to insulin, which is a hormone that allows the body to absorb glucose into human cells for energy
    .


    A decrease in the response to insulin may cause blood sugar levels to rise and cause the body to produce more insulin, which in turn causes the body to produce more androgens


    Recently, a study led by the University of Birmingham revealed for the first time that birth control pills can reduce the risk of type 2 diabetes in women with polycystic ovary syndrome (PCOS) by more than a quarter
    .


    Research published in " Diabetes Careon"


    Diabetes Diabetes Care women with PCOS suffer from diabetes, abnormal blood sugar twice the risk of type 2 or normal .


    Balachandran Kumarendran et al, Polycystic Ovary Syndrome, Combined Oral Contraceptives, and the Risk of Dysglycemia: A Population-Based Cohort Study With a Nested Pharmacoepidemiological Case-Control Study, Diabetes Care (2021).


    DOI: 10.
    2337/dc21-0437

    Balachandran Kumarendran et al, Polycystic Ovary Syndrome, Combined Oral Contraceptives, and the Risk of Dysglycemia: A Population-Based Cohort Study With a Nested Pharmacoepidemiological Case-Control Study, Diabetes Care (2021).


    They found that compared with women without polycystic ovary syndrome, women with polycystic ovary syndrome had twice the risk of developing type 2 diabetes or pre-diabetes
    .


    Hirsutism and high androgen levels are important risk factors for type 2 diabetes and prediabetes


    Compared with women without polycystic ovary syndrome, women with polycystic ovary syndrome have twice the risk of developing type 2 diabetes or pre-diabetes


    Professor Wiebke Arlt, Director of the Institute of the University of Birmingham, said: "We have learned from small studies in the past that women with polycystic ovary syndrome have an increased risk of type 2 diabetes
    .


    Now, we have been able to learn from a very large The demographic studies provide new evidence, showing for the first time that we have a potential treatment option, combined with oral contraceptives to prevent this very serious health risk


    prevention

    Dr.
    Michael O'Reilly, Clinical Associate Professor of the University of Health Sciences, added: "We hypothesize that contraceptive pills reduce the risk of diabetes by suppressing androgens
    .


    How does this work? The pills contain estrogen, which can increase a hormone called sex hormone in the blood.


    Anuradhaa Subramanian, the first author of the University of Birmingham, added: "One in 10 women suffers from polycystic ovary syndrome, a lifelong metabolic disorder, and it is extremely important to find ways to reduce its associated health risks
    .


    "

    Every 10 women there who suffers from polycystic ovary syndrome, which is a lifelong metabolic disorders, to find ways to reduce its associated health risks are extremely important in every 10 women in there who suffers from polycystic Ovarian syndrome, which is a lifelong metabolic disorder, and finding ways to reduce its related health risks is extremely important

    Professor Krish Nirantharakumar of the Institute of Applied Health at the University of Birmingham added: "The data also emphasizes that normal-weight women
    with polycystic ovary syndrome also face an increased risk of type 2 diabetes and pre-diabetes .


    This is the same as the previously discovered polycystic ovary syndrome.
    The increased risk of non-alcoholic fatty liver in women of normal weight is similar, further challenging the view
    that the metabolic complications associated with polycystic ovary syndrome are only related to obesity .
    These data indicate that obesity may be a specific factor of polycystic ovary syndrome
    .
    "

    Normal-weight women with polycystic ovary syndrome also face an increased risk of type 2 diabetes and pre-diabetes
    .
    Normal-weight women with polycystic ovary syndrome also face an increased risk of type 2 diabetes and pre-diabetes
    .
    Non-alcoholic fatty liver

    Reference materials:

    Balachandran Kumarendran et al, Polycystic Ovary Syndrome, Combined Oral Contraceptives, and the Risk of Dysglycemia: A Population-Based Cohort Study With a Nested Pharmacoepidemiological Case-Control Study, Diabetes Care (2021).
    DOI: 10.
    2337/dc21-0437

    Balachandran Kumarendran et al, Polycystic Ovary Syndrome , Combined Oral Contraceptives, and the Risk of Dysglycemia: A Population-Based Cohort Study With a Nested Pharmacoepidemiological Case-Control Study, Diabetes Care (2021) DOI:.
    10.
    2337 / dc21-0437 in this message
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