A variety of antibiotic courses are associated with the failure of pediatric treatment

children prescribed more than two courses of antibiotics a year for coughing, sore throat and ear pain are less likely to respond to subsequent treatments, according to a new report in the British Journal of General Medicine.
A group study based on statistics from the Clinical Practice Research Data Chain identified UK primary care data for children aged 1 to 5 between 2009 and 2016, excluding children who needed long-term antibiotics to treat chronic respiratory diseases such as tuberculosis.
Analysis data showed that 114,329 children who had been treated with antibiotics for acute respiratory infections during the study period were 3 percent more likely to respond to follow-up treatments than 114,329 children who had received a course of treatment in the previous year; Students who received at least two courses were 32 percent more likely to fail to respond.
More specifically, the study found a total failure rate of 1.2% out of 1,377 recorded medical records.
“ Unfortunately, antibiotics kill many of the beneficial bacteria that are commonly present in children - such as those in the gut that are critical to normal health," George Germanos, a postdoctoral researcher at Baylor College of Medicine, told Parent-Child Science.
He continued, "This healthy bacterial population is called the microbiome. Damaged microbiomes can cause harmful bacteria to overgrow and cause harm. ”（cyy123.com）