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AACR 2022: BioNTech's CAR-T cell therapy for solid tumors has proven efficacy

 Last Update: 2022-05-18
 Source: Internet
 Author: User

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Preliminary first-in-human trial data for BioNTech's CAR-T cell product, either as a monotherapy or in combination with an mRNA vaccine called CARVac, show that the therapy appears to be safe and shows early-stage progress in patients with advanced solid tumors Efficacy signs

CAR-T

CAR-T cell therapy has revolutionized the treatment options for hematological malignancies.

FDA Leukemia Lymphoma

Among 14 patients with relapsed or refractory advanced, CLDN6 ⁺ solid tumors, evaluable for efficacy 6 weeks after infusion of CAR-T cell therapy, 4 patients with testicular cancer and 2 patients with ovarian cancer experienced partial responses (PR), The overall response rate was nearly 43 %

immunity

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