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    Home > Active Ingredient News > Antitumor Therapy > AACR 2022: NK Cells and Bispecific Antibody AFM13 Complexes Consistently Induce Lymphoma Remission

    AACR 2022: NK Cells and Bispecific Antibody AFM13 Complexes Consistently Induce Lymphoma Remission

    • Last Update: 2022-05-18
    • Source: Internet
    • Author: User
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    The complex of the bispecific antibody AFM13 with NK cells continued to induce remission in patients with relapsed CD30 + lymphoma


    + lymphoma

    AFM13 is able to target CD16A and CD30, pre-complexed with cord blood-derived allogeneic NK cells in CD30 + relapsed or refractory Hodgkin lymphoma and non-Hodgkin lymphoma patients with median prior treatment Line is 7


    + The median prior line of therapy for these patients was 7 The median prior line of therapy for these patients was 7

    After undergoing immune cell dissection, subjects received two cycles of AFM13-NK cell complexes, up to 100 million cells/kg, administered to 13 patients and selected for Phase II evaluation


    immunity

    Of the 19 evaluable patients, 17 responded to treatment, resulting in an overall response rate (ORR) of 89%


    Of the 19 evaluable patients, 17 responded to treatment, resulting in an overall response rate (ORR) of 89%


     

    Original source:

    Original source:

    https://firstwordpharma.


    https://firstwordpharma.
    com/story/5545475 https://firstwordpharma.
    com/story/5545475

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