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The 12-week randomized, double-blind, placebo-controlled trial, which aims to determine the effectiveness and safety of probiotic mixtures in reducing the severity of psoriasis, was published online in Acta Derm Venereol.
study included 90 adults aged 18-70 with plaque-like psoriasis, randomly divided into probiotic and placebo groups.
in the 12-week follow-up, the psoriasis area and severity index decreased by up to 75 percent in 66.7 percent of patients in the probiotic group and 41.9 percent in the placebo group.
relevant clinical differences were observed in the Physicians Global Assessment Index.
48.9 percent of people in the probiotic group had a score of 0 or 1, while the placebo group had a score of 30.2 percent.
6 months after the end of the study showed a lower risk of recurrence after ingesting a probiotic mixture.
, the analysis of the gut microbiome confirms the efficacy of probiotics in regulating the composition of the microbiome.
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