Advances in research on Arabidopsis genome assembly

Advances in research on Arabidopsis genome assembly

Advances in research on Arabidopsis genome assembly Advances in research on Arabidopsis genome assembly Schematic diagram of the Arabidopsis genome assembly process
.
The researcher provided a schematic diagram of the Arabidopsis genome assembly process
.
Researcher Professor Ye Kai and Associate Professor Yang Xiaofei of the School of Computer Science published research in the "Journal of Genome Proteomics and Bioinformatics" as co-corresponding authors.
Based on the experience accumulated in the assembly of opium poppy and human genome, they designed a comprehensive use of different sequencing technologies Advantageous hybrid sequencing strategy, proposed a new strategy for sequence replacement with bacterial artificial chromosomes as anchor points, and realized the high-quality Arabidopsis genome Col-XJTU with only two gaps .
Moreover, the genome has completed the gapless assembly of the centromeres of chromosomes 3, 4, and 5, and completed the assembly of most centromeres of chromosomes 1 and 2 .
In addition, the base accuracy and structural accuracy of this genome are both higher than the current reference genome TAIR10.
1.
The base accuracy is 99.
9999% .
https://doi.
org/10.
1016/j.
gpb.
2021.
08.
003