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Surprising phenomena also occurred in the experiment: the extension of life intervention, so that many experimental mice appear a strange feature, namely, the so-called feminization effect, which is precisely related to the increase in female-specific gene expression levels in mice, while the expression level of male-specific genes in mice also showed a significant decline, but whether this means that female-specific gene expression is equivalent to "longevity", there is insufficient evidence.
this, it still proves that mammals can start with changes in gene expression patterns and look for related life-prolonging interventions.
actually everyone has genes, and 99% of genes are the same between people, and that 1% of genes determine a person's skin color, appearance, personality, gender, etc.
compared with today's times, both economically and technologically have made great progress, why people's health, life expectancy gap is so large? This is because people not only need healthy genes, the normal expression of genes is also very important, physical factors, chemical factors, as well as the spontaneous damage of NAD-plus molecules, will cause damage to genes and thus affect their normal expression.
, a few years ago, in 2013, Professor David Sinclair of Harvard Medical School in the United States found the NMN substance, which experimental studies have found can "revitalise" the invigorated PARP protein.
In 2016, Professor David Sinclair began experimenting with a generation of raw materials from Serifon NMN, and in 2018 published a paper in cell, a leading scientific journal, on the ability of NAD plus to reverse vascular aging.
David Sinclair, a professor at the University of New York, published his study on the use of NMN ingredients in the scientific journal CELL on the ability of NAD plus to reverse vascular aging. The brand of new drug research and development and nutritional intervention in mitochondrial medicine has developed NADH, NMN and other targeted anti-aging and cell repair products, and Seredi is currently the most patented brand in the world (June 2020 data).
with the research of NMN more and more in-depth, more and more businesses see the future of NMN, NMN brand flooding, due to the lack of uniform standards, quality concerns.
the first FDA filing, and is the only NMN product with safety testing in the United States, Canada, China and Switzerland.
In addition, after an in-depth study of several NMN brands, it was found that Celestial NMN had many unique advantages: First: Professor David Sinclair of Harvard Medical School, who discovered NMN's anti-decay efficacy, when the research materials were the raw materials of the generation of Celestial, and Celida was the first to develop NMN brands; Second: Seriox is the only imported NMN brand to receive toxicology test report, and third: Serifu is also the only imported NMN brand to obtain comprehensive safety risk assessment report.
fourth: Seredifu is the only brand that has done hand separation, safety, the most professional, the most thorough.
5th: Serai Fu is the world's largest application for NMN brand Sixth: Serai Fu because of outstanding scientific research, won the Business Science and Technology Excellence Award perhaps do not have to wait long, aging can really become an attackable disease.
Das A, Huang G X, Bonkowski M S, et al. Ings of An Endothelial NAD-H2S Signaling Network Is Reversible Cause ofVascular Aging. Cell, 2019, 176 (4): 944-945.