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    Home > Active Ingredient News > Immunology News > After receiving $100 million in financing, Rongchang Bio's fusion protein TACI-Fc treatment of lupus lupus gets FDA fast-track designation

    After receiving $100 million in financing, Rongchang Bio's fusion protein TACI-Fc treatment of lupus lupus gets FDA fast-track designation

    • Last Update: 2020-05-29
    • Source: Internet
    • Author: User
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    RemeGen announced that the U.SFood and Drug Administration (FDA) has granted fast-track designations for its new recombinant TACI-Fc fusion protein RC18 to treat systemic lupus erythematosus (SLE)With its novel two-target mechanism, RC18 showed a statistically significant improvement in patientsRC18 is a new recombinant TACI-Fc (cross-membrane activator and calcium-to-procycline ligand interaction molecule) fusion protein for the treatment of autoimmune diseasesRC18 has a dual targeting mechanism that inhibits the development and survival of pulp cells and mature B cells associated with a variety of autoimmune diseasesRC18 works by binding to two cellular signaling molecules: B lymphocytic stimulator (BLyS) and proliferation-induced ligand (APRIL)currently, RC18 is being studied in a number of late-stage clinical trials of autoimmune diseases, including systemic lupus erythematosus, rheumatoid arthritis and optic neurospinalitisDr Kenmin Fang, founder and CEO of RemeGen, said: 'SLE is a chronic autoimmune disease that attacks healthy tissues and is estimated to affect between 322,000 and 1.5 million people in the United StatesPatients have very limited treatment options available, and fast-track designations give RemeGen the opportunity to help those affected by the disease by providing advanced therapiesTheRemeGen's recently completed $100 million financing, led by Lilly Asia Ventures and Blue Lake Capital
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