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Alzheimer's disease (AD) affects more than 40 million people worldwide.
There are already more than 10 million AD patients in China, and there is currently no effective treatment that can be cured
.
A recent study shows that elderly people who are indifferent to or lack interest in daily activities are more likely to develop dementia
Alzheimer's disease (AD) affects more than 40 million people worldwide.
People with severe apathy are 80% more likely to have dementia
In fact, neuropsychiatric symptoms (NPS) are extremely common in AD and other types of dementia, and are usually more troublesome than cognitive symptoms
.
These symptoms include agitation, aggression, delusions, hallucinations, paranoia, wandering, depression, apathy, disinhibition, and sleep disturbances
At present, the NPS of early dementia is considered to predict the high risk of dementia progression
.
However, it is not clear whether this risk is similar between AD and non-AD dementia and different NPS
At present, the NPS of early dementia is considered to predict the high risk of dementia progression
The results showed that the existence of NPS is related to the risk of progression to severe dementia.
Among them, the risk of AD progression (HR=1.
4, 95%CI: 1.
1-1.
6) increased by 40%, and non-AD (HR=0.
9, 95% CI: 0.
5-1.
5) Progress risk is irrelevant
.
When comparing various NPSs, the 7 NPSs in AD are related to disease progression.
The existence of NPS is related to the risk of progression to severe dementia.
NPS in early dementia--especially in AD patients--can be a useful prognostic marker of disease progression
references:
Tau Ming Liew, Neuropsychiatric symptoms in early stage of Alzheimer's and non-Alzheimer's dementia, and the risk of progression to severe dementia, Age and Ageing, 2021;, afab044, https://doi.
Neuropsychiatric symptoms in early stage of Alzheimer's and non-Alzheimer's dementia, and the risk of progression to severe dementia, leave a message here
