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    Home > Active Ingredient News > Digestive System Information > AJG: Association between long-term statin use and total cholesterol levels and colorectal cancer risk

    AJG: Association between long-term statin use and total cholesterol levels and colorectal cancer risk

    • Last Update: 2022-02-17
    • Source: Internet
    • Author: User
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    In the United States, statins are the most commonly used cholesterol -lowering drugs, and for the past few decades, statins are a lipid-lowering drug commonly used to treat hypercholesterolemia and reduce cardiac mortality and morbidity


    In the United States, statins are the most commonly used cholesterol -lowering drugs, and for the past few decades, statins are a lipid-lowering drug commonly used to treat hypercholesterolemia and reduce cardiac mortality and morbidity


    Eligible participants (100,300 women and 47,991 men) from the Nurses' Health Study and the Health Professionals Follow-up Study cohort were followed for up to 24 years


    In this study of 2,924 CRC cases documented throughout follow-up, researchers found that longer statin use was associated with a higher risk of colon cancer (HR 1-5 years, 1.


    Colon Cancer Screening

    Figure: The relationship between statins and CRC

    The results of this study do not support a benefit of statins in CRC chemoprevention or any association between total cholesterol levels and CRC risk


    The results of this study do not support a benefit of statins in CRC chemoprevention or any association between total cholesterol levels and CRC risk


    Zhang, Yin.


    Long-Term Statin Use, Total Cholesterol Level, and Risk of Colorectal Cancer: A Prospective Cohort Study.


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