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AJG: Comparison of the efficacy of biologics for endoscopic healing of the ileum and colon in patients with Crohn's disease

 Last Update: 2022-08-19
 Source: Internet
 Author: User

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Crohn's disease (CD) is an inflammatory bowel disease (IBD) characterized by transmural inflammation in any area of the gastrointestinal trac.

This trial pooled analysis of 299 CD patients from 4 clinical trial.

Adalimumab (17/61 [29%], [OR]: 79, 95% [CI]: 77–195, P= 004) and infliximab (39/141 [27%], aOR: 59, 95% CI: 48–122, P = 008) had a higher incidence of EH at 1 yea.

This study initially demonstrated that TNF-α antagonists (adalimumab and infliximab) were generally superior to vedolizumab and ustekinumab in achieving 1-year EH in patients with moderate-to-severe C.

Original source:

Narula, Neera.

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