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Introduction and Purpose: Nocturnal gastroesophageal reflux (nGER) symptoms are usually associated with sleep disruptionMost studies that try to understand the relationship between sleep, wakefulness and nGER events are done through accelerometersHowever, the technique has limited ability to accurately determine the time correlation between sleep and reflux eventsThe purpose of this study was to examine the tempor relationship between nGER events and sleep wake-up/wake-up using a high-resolution laboratory polygone sleep map (PSG)method: The researchers simultaneously performed 24-hour pH/impedance monitoring and laboratory PSG on individuals between the ages of 18 and 70 who underwent gastroscopy for 12 monthsDetermine the time relationship between each nGER event and sleep/wake/wake.comresults: The researchers analyzed data from 25 individuals, 64% of whom had nGER seizures (5 to 5 events per person, ranging from 1-18), of which 64% had obstructive sleep apnea (OSA, average apnea-deficiency index 20 x 11, range 6-44 events/hour)There was no difference in the severity of sleep time, sleep efficiency, sleep structure, wake/wake or sleep apnea in those who had nGER and those without nGERMost nGER events (82%) occurred during the PSG periodWake-up/wake-up (73/76) before almost all events occur, while fewer events (15/76) have been woken/waked after the eventdiscussion: This study shows that nGER does not appear to cause sleep arousal, but rather sleep-induced nGERShepherd, KellyEt alTemporal Relationship Between Night-Time Gastroeal Reflux Events and Arousals From Sleep.
American journal of Gastroenterology2020 Source: MedSci Original