AJKD: Incidence and outcome of COVID-19 in CKD patients

Coronavirus disease ( COVID-19 ) in 2019 has a particularly serious impact on patients with chronic kidney disease (CKD) and other chronic diseases
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COVID-19

Recently, the authoritative journal of nephrology, Am J Kidney Dis, published a research article that aims to evaluate the incidence and outcome of COVID-19 in CKD patients
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The researchers searched MEDLINE, EMBASE and PubMed, and the search time is up to February 2021, for systematic reviews and meta-analysis
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The study population is CKD patients with or without COVID-19

The analysis included 348 studies (382,407 COVID-19 and CKD participants; 1,139,979 CKD participants)
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Based on low-quality evidence, the incidence of COVID-19 in CKD patients receiving dialysis treatment is higher (105 cases per 10,000 people per week; 95% CI 91-120; 95% prediction interval [PrI] 25-235; 59 Studies; 468,233 participants), compared to CKD patients who do not require renal replacement therapy (16 per 10,000 people per week; 95% CI 4-33; 95% PrI 0-92; 5 studies; 70683 Participants) and kidney or pancreas-kidney transplant recipients (23 per 10,000 people per week; 95% CI 18-30; 95% PrI 2-67; 29 studies; 120,281 participants)

Compared with CKD patients or kidney or pancreas-kidney transplant recipients who do not require renal replacement therapy, CKD patients undergoing maintenance dialysis may have a higher incidence of COVID-19
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CKD patients with COVID-19 may have a higher mortality rate than CKD patients without COVID-19

Compared with CKD patients or kidney or pancreas-kidney transplant recipients who do not require renal replacement therapy, CKD patients undergoing maintenance dialysis may have a higher incidence of COVID-19

Original source:

Edmund YM.

Incidence and Outcomes of COVID-19 in People With CKD: A Systematic Review and Meta-analysis in this message