AJRCCM: Is blood sugar control the secret to controlling tuberculosis?

As we all know, diabetes has a great harmful effect on tuberculosis patients

diabetes

Recently, in a study published by AJRCCM, Liu and colleagues added additional nuances to the relationship between diabetes and tuberculosis, indicating that in tuberculosis patients without diabetes, common blood sugar changes may be due to the patient's response to tuberculosis treatment.

In tuberculosis patients without diabetes, common blood glucose changes may be an important indicator of the patient's response to tuberculosis treatment

The study included 405 Chinese patients newly diagnosed with tuberculosis, and continuously measured their fasting blood glucose (fasting blood glucose) at the time of diagnosis, the third and sixth months of treatment, and the second and fourth months after the completion of treatment.

The blood glucose trajectory showed that before, during, and/or after tuberculosis treatment, nearly half (49.

Known or newly diagnosed diabetes are more likely to experience treatment failure in patients with known or newly diagnosed diabetes patients are more likely to experience treatment failure

Even more surprising is that patients with transient hyperglycemia and unstable blood sugar also have an increased chance of treatment failure (adjusted odds ratio, 4.

Transient hyperglycemia and the chance of treatment failure in patients with unstable blood sugar also increases the chance of therapy in patients with transient hyperglycemia and glycemic instability failure is also increased when including diabetes when including diabetes when the group increased the proportion of all treatment failure 80% (In the group, the proportion of all treatment failures increased to 80%

During the entire treatment process, the baseline fasting blood glucose measurement value or the average value of the fasting blood glucose measurement value will not identify different patterns of dynamic changes in fasting blood glucose

This study identified different blood glucose trajectories from the diagnosis of tuberculosis to the post-treatment stage, and evaluated the relationship between the blood glucose trajectory and the outcome of tuberculosis treatment

Fasting blood glucose track to capture the relationship between glycemic control and treatment outcomes nuances fasting glucose track to capture the relationship between glycemic control and treatment outcomes nuances beyond the standard two diabetes classification criteria other patient groups revealed increased risk of treatment failure beyond Diabetes criteria two classification criteria reveal other patient groups with increased risk of treatment failure

references:

references:

[1] Liu Q, You N, Pan H, Shen Y, Lu P, Wang J, Lu W, Zhu L, Martinez L.

[1] Liu Q, You N, Pan H, Shen Y, Lu P, Wang J, Lu W, Zhu L, Martinez L.

[2] Huddart S, Savic RM, Cattamanchi A.

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