Alz Res Therapy: Healthy Eating, Lower Dementia Risk

Diet has gained increasing attention as a target for developing opportunities to prevent dementia because it affects several fundamental mechanisms of dementia, including oxidative stress, inflammation, and vascular abnormalities
.

As a result, various studies have linked adherence to a healthy eating pattern to a slower rate of cognitive decline and a lower risk of dementia

prevent blood vessels

Although this healthy eating pattern may be suboptimal for brain health
.

Therefore, the Mediterranean- Dietary Approaches to Stop Hypertension (DASH) Intervention for Neurodegenerative Delay (MIND) diet has been developed to uniquely emphasize the relationship between brain health and brain health.

hypertension

First, the mean follow-up time in previous studies was 4.
5 to 6.
6 years, which is broadly consistent with the prodromal stages of dementia
.

During this phase of progressive cognitive impairment, eating habits may worsen, for example, due to depressive symptoms and olfactory disturbances

Second, studying dietary patterns in observational studies is notoriously difficult because it is always disturbed by life>
.

Although previous studies controlled for life>

The Rotterdam Study was a population-based prospective study that assessed dietary intake in a largely non-overlapping sample from 1989-1993 and 2009-2013
.

In this way, Tosca OE de Crom et al.
, from the University of Lutheran University, explored the association between adherence to the MIND diet and dementia risk in these two settings separated by 20 years, over the cumulative follow-up interval
.

In addition, to find out whether the MIND diet is indeed more targeted for brain health than other healthy diets, the association between adherence to two other healthy diets and dementia risk was also investigated

In the population-based Rotterdam study, they used a validated food frequency questionnaire to assess the quantification of Dietary intake was assessed
.

We calculated the MIND diet score and used a Cox model to investigate its association with all-cause dementia risk; onset of all-cause dementia was recorded through 2018

During a mean follow-up period of 15.
6 years from Baseline I, 1188 participants developed dementia
.

A higher MIND diet score at baseline I was associated with a lower risk of dementia in the first 7 years of follow-up (hazard ratio (HR) [95% confidence interval (CI)], increase per standard deviation (SD) 0.

The mean follow-up from Baseline II was 5.
9 years, during which 248 participants developed dementia
.

During each follow-up interval, higher MIND diet scores at baseline II were associated with lower dementia risk, but the association weakened slightly over time (HR [95% CI] at 7 years of follow-up, 0.

The mean follow-up from Baseline II was 5.
9 years, during which 248 participants developed dementia
.

The MIND diet score at baseline II was more closely associated with dementia risk than the MIND diet score at baseline
I.

The significance of the study was its finding that better adherence to the MIND diet was associated with a reduced risk of dementia in the first few years of follow-up , but this may be explained in part by reverse causality and residual life>
.
Further research is needed to reveal the extent to which the MIND diet affects dementia risk
.

Better adherence to the MIND diet associated with reduced dementia risk in first years of follow-up

Original source:
[de Crom TOE, Mooldijk SS, Ikram MK, Ikram MA, Voortman T.
MIND diet and the risk of dementia: a population-based study.
Alz Res Therapy.
2022;14(1):8.
doi:10.
1186 /s13195-022-00957-1](https://doi.
org/10.
1186/s13195-022-00957-1)

MIND diet and the risk of dementia: a population-based study.
Alz Res Therapy.
2022;14(1):8.
doi:10.
1186/s13195-022-00957-1](https://doi.
org/10.
1186/ s13195-022-00957-1)

 

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