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    Home > Active Ingredient News > Study of Nervous System > Alzheimer&Dementia: Associations between vascular risk factors, neuroimaging biomarkers and the development of dementia

    Alzheimer&Dementia: Associations between vascular risk factors, neuroimaging biomarkers and the development of dementia

    • Last Update: 2022-05-23
    • Source: Internet
    • Author: User
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    Numerous studies have investigated the effect of individual cardiovascular risk factors, including older age, diabetes , hypertension , smoking, and hypercholesterolemia , on dementia risk, with mixed results


    Numerous studies have investigated the effect of individual cardiovascular risk factors, including older age, diabetes , hypertension , smoking, and hypercholesterolemia , on dementia risk, with mixed results


    Previously used the Framingham General Cardiovascular Risk Score (FGCRS), a predictive algorithm to assess cardiovascular risk burden and risk of developing cardiovascular disease by combining demographics (i.


    Currently, little is known about how prior vascular risk factor (VRF) status affects brain health in later life


    Currently, little is known about how prior vascular risk factor (VRF) status affects brain health in later life


    RESULTS : African Americans exhibited baseline cardiovascular risk factors, incidence of aging and dementia (CAIDE), Framingham Stroke Risk Profile (FSRP), and atherosclerotic cardiovascular disease risk compared with whites Estimated (ASCVD) score was higher


    Higher baseline VRF scores were associated with lower cortical thickness and larger WMH volume, whereas FSRP and CAIDE were associated with Aβ


    The findings suggest that the interaction of multiple vascular and Alzheimer's pathological factors underlies neurodegeneration and cognitive decline


    The findings suggest that the interaction of multiple vascular and Alzheimer's pathological factors underlies neurodegeneration and cognitive decline


    references:

    references:

    Associations among vascular risk factors, neuroimaging biomarkers, and cognition: Preliminary analyses from the Multi-Ethnic Study of Atherosclerosis (MESA).


    Associations among vascular risk factors, neuroimaging biomarkers, and cognition: Preliminary analyses from the Multi-Ethnic Study of Atherosclerosis (MESA).
    https://doi.
    org/10.
    1002/alz.
    12429 Associations among vascular risk factors, neuroimaging biomarkers, and cognition : Preliminary analyses from the Multi-Ethnic Study of Atherosclerosis (MESA).
    https://doi.
    org/10.
    1002/alz.
    12429

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