Alzheimer Dementia: The higher the resting heart rate, the higher the risk of dementia in the future

The global burden of dementia is increasing rapidly, and 43 million people were affected in 2016

Dementia has a devastating effect on the quality of life of the elderly, their families and society as a whole

There is evidence that cardiac vascular diseases (CVDs) and development-related dementia, including Alzheimer's disease, may be due to common risk factors, atherosclerosis changes in arterial rigid, micro-embolism and brain hypoperfusion

A large amount of evidence consistently shows that an increase in resting heart rate (RHR) can predict future cardiovascular disease events, surpassing traditional cardiovascular disease risk factors

Because the increase in RHR is related to the high risk of some cardiovascular diseases, such as ischemic heart disease (IHD), atrial fibrillation (AF), heart failure (HF) and stroke, and these cardiovascular diseases are known as dementia Risk factors

In this way, Yume Imahori and others of the Caroline School of Medicine, the purpose of a population-based cohort study is to investigate the relationship between elevated RHR and dementia in the general elderly population

The core hypothesis is that elevated RHR is related to the increased risk of dementia and overall cognitive decline in the elderly, and their relationship may exist independently of cardiovascular risk factors and CVDs

They tried to test our hypothesis by examining the relationship between RHR and the cognitive decline and dementia of the elderly with and without epidemics and CVDs

This population-based cohort study included 2147 SNAC-K participants (age ≥60 years) who did not have dementia and were followed up regularly from 2001-2004 to 2013-2016

They found that the multi-adjusted hazard ratio between RHR ≥ 80 (and 60-69) bpm and dementia was 1.

After excluding participants with epidemic and event cardiovascular diseases, this association remained significant

The important significance of this study lies in the discovery: in the general elderly population, a higher RHR is associated with an increase in the risk of dementia and a rapid decline in cognitive ability, and has nothing to do with CVDs

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