Alzheimer&Dementia: The real hammer, the significant decline in cognitive function after COVID-19!

As more and more people recover from SARS-CoV-2 infection
, there is an urgent need to study the medium- and long-term consequences of the disease .
There is growing evidence that some patients show symptoms such as fatigue, delirium or cognitive aspects after the acute infection phase, often referred to as "long-term COVID"

To clarify cognitive changes in post-COVID-19 patients, a systematic review and meta-analysis of the cognitive impact of COVID-19 patients without a history of cognitive impairment was conducted from the Frani Division of Cognitive Neurology in Buenos Aires, Argentina.
, the results were published in the journal Alzheimer & Dementia
.

Search in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines in Medline/Web of Science/Embase from January 1, 2020 to December 13, 2021
.
A meta-analysis of Montreal Cognitive Assessment (MoCA) total scores was performed comparing recovered COVID-19 and healthy controls

Among 6202 articles, 27 studies were included, involving 2049 people (mean age = 56.
05 years, assessment time ranging from acute phase to 7 months post-infection)
.
Impairments in executive function, attention and memory have been found in post-COVID-19 patients

In conclusion, compared with healthy controls, patients infected with COVID-19 showed a significant decrease in overall cognitive performance within 7 months of infection

references:

Changes in cognitive functioning after COVID-19: A systematic review and meta-analysis.