Alzheimers Dement: A new study from Fudan University suggests that 6-7 hours of sleep a night can prevent dementia, with 10 o'clock sleeping best.

Recently, Fudan University affiliated Huashan Hospital Neurology Tulip Tai, together with Qingdao University Qingdao City Hospital Neurology Tanlan Professor team, over a period of 3 years, in nearly a thousand people in a large clinical cohort study found that: frequent sleep during the day, lack of sleep at night or sleep too much can increase the risk of cognitive impairment, and sleep 6 hours to 7 hours per night can reduce the risk of cognitive impairment, sleep at 10 o'clock every night the best effect.
the risk of cognitive impairment increases significantly if you sleep less than 4 hours or more at night.
study was recently published in the journal Alzheimer's and Dementia under the title: Sleeps and cerebrospinal fluid biomarkers of Alzheimer's disease pathology in the journal Cooly intact older adults: The CABLE study.
According to Professor Tulip Tai, they first established a large-scale database of clinical studies of cognitive impairment and a database of biological samples, and based on the establishment of the Chinese Chinese Alzheimer's Biomarkers and Lifestyle Study), they explored in depth the effects of various sleep characteristics on pathophysiological changes in Alzheimer's disease.
's team confirmed for the first time the U-shaped relationship between nighttime sleep time and alzheimer's pathology in middle-aged and older people: lack of or too much sleep can promote abnormal deposition of amyloid proteins in the body, which is a key factor in the development of Alzheimer's disease and one of the core pathological characteristics of Alzheimer's disease.
daytime dysfunction (e.g. frequent daytime sleep) can also promote abnormal deposition of amyloid proteins in the body.
optimal sleep patterns were 6 to 7 hours of sleep at 10 p.m. each night, with the lowest levels of abnormal deposition of amyloid protein in the brain.
Tuliptai said the team also mapped evidence of a link between sleep and the risk of cognitive impairment, including Alzheimer's disease, and found that 10 sleep characteristics (disorders) contribute to cognitive impairment, six of which are supported by moderate-intensity evidence, including insomnia, sleep division, daytime dysfunction, and excessive bedtime.
Further dose response analysis found a U-shaped relationship between nighttime sleep time and Alzheimer's risk: the optimal nighttime sleep duration may be between 5.6 and 7 hours;
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