Alzheimer's & Dementia: Head injury is related to tau deposition in the brains of MCI and AD patients 

Statistics show that Alzheimer's disease (AD) affects more than 5.

Traumatic brain injury (TBI) associated with head injury (HI) is a risk factor for dementia, including AD and other neurodegenerative diseases

Neuroimaging studies of TBI patients showed abnormal white matter microstructures, as well as gray matter and white matter atrophy in symptomatic CTE patients

A study using [18F]flortaucipir tau PET on small samples of suspected CTE and/or other recurring HI due to exercise or military exposure showed that [18F]flortaucipir combined with the frontal, occipital, and temporal lobes in the subcortical area Increase

Currently, the potential link between head injury (HI) and dementia is not entirely clear

Recently, researchers used amyloid and [18F] fluorouracil positron emission tomography, HI history data, Alzheimer’s Disease Neuroimaging Initiative, and the Indiana Memory and Aging Research Cognitive Test to test 752 subjects Cognition and tau deposition were compared, of which 302 had cognitive impairment and 450 had no cognitive impairment (CN)

According to the diagnosis Tau deposition of the population and a history of head injury

In this study, 63 people (38 CN, 25 impaired) reported a history of HI

Original source:

Shannon L.