Alzheimers & Dementia: Investigating the relationship between cancer and dementia risk

Driver et al.
found in a large prospective community cohort study that cancer has been determined by several epidemiological studies to have a protective effect on dementia, especially Alzheimer’s disease (AD)
.

Similarly, a prospective cohort in the United Kingdom found that cancer not only reduces the risk of any AD-related dementia, but also reduces the risk of future cancer by up to 70%

Driver et al.

The argument against the obvious protective effect has been discussed in the previous literature

Although there are statistical methods to resolve many potential deviations, most previous studies are limited to the use of standard survival models or simulation studies, which ignore the potential role of competing events

The data used in this study comes from the Memento cohort, a French multicenter cohort that tracks people with mild or isolated cognitive complaints, with a median of 5 years
.

The disease-death model (IDM) was used to estimate metastasis-specific risk ratios (HRs) and 95% confidence intervals (CI) for incidental cancers associated with dementia since the beginning of the study

The data used in this study comes from the Memento cohort, a French multicenter cohort that tracks people with mild or isolated cognitive complaints, with a median of 5 years

•  The analyzed cohort population (N=2 2 5 8) excluded 65 cases without complete follow-up data
  
  This research supports the protective relationship between cancer and dementia and encourages further research to understand the underlying underlying mechanisms
  
  Literature source: https://doi.
  80599.
  net/10.
  1002/alz.
  12308 https://doi.
  80599.
  net/10.
  1002/alz.
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