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In areas where non-western diets are used, the efficacy and related factors of low-fermentable oligosaccharides, disaccharides, monosaccharides and polyols (LFD) diets compared with traditional dietary advice (TDA) are not yet clear.
The study randomly divided 108 Chinese patients with IBS-D who met Rome III criteria into two groups: LFD group and TDA group.
Irritable bowel syndrome
The daily average symptom scores of each treatment group in the first week and the third weekend were compared with baseline individual symptoms and overall discomfort.
The daily average symptom scores of each treatment group in the first week and the third weekend were compared with baseline individual symptoms and overall discomfort.
The changes of SCFA in patients' feces before and after LFD or TDA.
The changes of SCFA in patients' feces before and after LFD or TDA.
Changes in fecal microbial diversity and relative abundance of all selected patients before and after LFD or TDA.
Changes in fecal microbial diversity and relative abundance of all selected patients before and after LFD or TDA.
Raw data and models that predict the probability of a patient's response to LFD or TDA.
Raw data and models that predict the probability of a patient's response to LFD or TDA.
The microbial spectrum of responders and non-responders and healthy people on LFD is different.
The microbial spectrum of responders and non-responders and healthy people on LFD is different.
Changes in microbial spectrum after 3 weeks of LFD treatment.
Changes in microbial spectrum after 3 weeks of LFD treatment.
In short, both LFD and TDA can improve the symptoms of Chinese IBS-D patients.
In short, both LFD and TDA can improve the symptoms of Chinese IBS-D patients.
oup.
com/ajcn/advance-article-abstract/doi/10.
1093/ajcn/nqab005/6178924?redirectedFrom=fulltext" target="_blank" rel="noopener">Zhang Yawen,Feng Lijun,Wang Xin et al.
Low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols diet compared with traditional dietary advice for diarrhea-predominant irritable bowel syndrome: a parallel-group, randomized controlled trial with analysis of clinical and microbiological factors associated with patient outcomes.
[J] .
Am J Clin Nutr, 2021, undefined: undefined.
com/ajcn/advance-article-abstract/doi/10.
1093/ajcn/nqab005/6178924?redirectedFrom=fulltext" target="_blank" rel="noopener">Zhang Yawen,Feng Lijun,Wang Xin et al.
Low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols diet compared with traditional dietary advice for diarrhea-predominant irritable bowel syndrome: a parallel-group, randomized controlled trial with analysis of clinical and microbiological factors associated with patient outcomes.
[J] .
Am J Clin Nutr, 2021, undefined: undefined.
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