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Obesity low-breathing syndrome (OHS) is associated with cardiac dysfunction.
, however, there was a lack of randomized trials to assess the effects of long-term non-invasional breathing (NIV) or continuous positive pressure on the heart structure and function of the evaluation of echoponic heart maps.
study conducted a secondary analysis of the largest OHS multi-center randomized controlled trial (Pickwick project; 221 OHS patients with severe obstructive sleep apnea) and compared the effectiveness of three-year NIV and CCPP changes in structure and functional echoponic heartbeats.
patients were subjected to thoracic 2D and Doppler echoptograms annually at baseline and for three consecutive years.
an echoctic heartbeat of each site, and the examiner did not understand the distribution of treatment.
use a linear mixing effect model with treatment group and repeated measurement interaction to determine the difference between CPAP and NIV.
results analyzed 196 patients: 102 received CPAP treatment and 94 received NIV treatment.
the use of CPAP, the systolic pulmonary pressure dropped from baseline 40.5 to 1.47 mm Hg to 35.3 x 1.33 mm Hg after 3 years. The pressure of the pulmonary arteries during the contraction period was reduced from 41.5 to 1.56 mm Hg to 35.5 to 1.42 (vertical change P 0.0001 in both treatment groups).
, there are no significant differences between groups.
NIV and CPAP therapy also improved left adulation dysfunction and reduced the diameter of the left adulation.
both NIV and CPAP can improve breathing function and difficulty breathing.
, the results show that long-term use of NIV and CPAP treatment can improve pulmonary hypertension and left ventilated dysfunction similarly in OHS patients with severe obstructive sleep apnea.
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