echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Biochemistry News > Biotechnology News > Amazing discovery: Alleles are different in paternal inheritance and maternal inheritance.

    Amazing discovery: Alleles are different in paternal inheritance and maternal inheritance.

    • Last Update: 2022-01-07
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    The research team focused on the H19 gene locus.


    "Although the general imprinting mechanism of the mouse H19 locus has been well established, it is not clear how the expression of H19 is affected by its own methylation status," explained Assistant Professor Hitomi Matsuzaki, who was responsible for this.


    Then, the research team hypothesized that by reversing H19 ICR, thereby reversing its direction, they could reduce H19 methylation, and they created mutant mice to test this


    "Our findings about maternal genetic alleles are quite unexpected, especially considering the father's data," said assistant professor Matsuzaki


    Further studies did not provide evidence that the methylation status of ICR is related to differences in the expression of H19 in maternal alleles


    In conclusion, Assistant Professor Matsuzaki and his colleagues provided convincing insights into the complex nature of mouse genome imprinting


    Hitomi Matsuzaki, Yu Miyajima, Akiyoshi Fukamizu, Keiji Tanimoto.



    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.