An analysis of the "god medicine" - resveratrol

Permanence has been the eternal pursuit of mankind since ancient times, Qin Shihuang sent 500 children and boys along with Xu Fu to overseas Penglai Xianshan in search of permanence medicine is an example.
With the progress of science and technology, scientists gradually discovered the secret of "long life" from lighthouse jellyfish, which return to the state of waterafter sexual maturity, and can repeat the process indefinitely, thus having the ability to "not grow old, not die".
, scientists have put forward the theor of "telomeres" and "free-form" the theorism, which expounds the "nature of long life", that is, to delay the aging of the body.
organs and tissues of the human body are made up of cells, which are divided into stem cells and non-stem cells.
body aging is caused by organ aging, which is caused by tissue aging, and tissue aging is caused by cell aging, especially stem cell aging.
people look forward to such a drug, do not need to be hospitalized injections, do not have to suffer pain, can slow down the body aging.
, people turned their attention to resveratrol.
is the true face of resveratrol? There are many different opinions, the results of different literature are not the same... About Resveratrol Resveratrol (3,4', 5-trihydroxydylene) is a polyphenol antitoxin found in a variety of plant species, such as peanuts, berries and grapes, most commonly found in the roots of Japanese tiger canes.
resveratrol has been used for inflammatory treatment in Asia for hundreds of years.
recent years, the reason red wine is considered healthy is that grapes contain the substance.
inspired by an event called the French Paradox.
The French Paradox was first proposed in an academic paper published in 1819 by an Irish doctor named Seymour Blair: the French love good food and eat a diet high in calories and cholesterol, but have a much lower risk of cardiovascular disease than people in English-speaking countries.
why is this happening? Surveys have found that locals often eat with tonin-rich wines.
red wine contains resveratrol, which has the effect of preventing blood clots, anti-inflammatory, promoting vascular dilation and inhibiting bacterial reproduction.
2. Effects of resveratrol structural resveratrol Cardiovascular disease is the leading cause of morbidity and mortality in the United States and is most commonly manifested in atherosclerosis.
studies show that resveratrol has the following effects: a. inhibit the oxidation of LDL isolated from normal blood pressure individuals; b. inhibit plate plate aggregation and reduce plateboard aggregation induced by adenosinediphosphate; c. In-body inhibition of smooth muscle cell proliferation; d. reduction of esophageal cancer cell proliferation; e. weakening of endothragm thickening and reduction of the average area of atherosclerotic plaques; f. dose dependence increased protein expression of tumor suppressor gene p53, heat shock protein HP27, pyroidase 1 and 2, induced nitric oxide and its altered subcellular distribution.
Figure 3. At the same time, resveratrol has the following effects: (1) Resveratrol has the following effects: (1) The anti-fever and pain-relief effect Resveratrol can be used in a variety of ways to treat heat and pain.
study by drugologists in rats showed that resveratrol gives the stomach mucosa the ability to resist stress ulcers caused by suppression of stomach secretion without affecting blood pressure.
(2) Anti-cancer effects . . . resveratrol affects the secontinct stage of cancer by regulating signal transductive pathways such as cell division and growth, apoptosis, inflammation, angiogenesis, and metastasis.
a systematic review of the anti-cancer activity of resveratrol and its derivatives in a 2010 article published in the journal Drug Discovery Today, suggesting that resveratrol and its derivatives have effective anti-cancer activity.
(3) Antioxidant Resveratrol is a natural antioxidant present in many plants, mainly by removing or inhibiting the production of free-form oxidation to inhibit lipid peroxidation, regulate antioxidant function of the associated enzyme activity and other mechanisms to play an antioxidant role.
When the blood content of resveratrol is 1.3 μg/mL and above, it can significantly inhibit the lipidized peroxidation of red blood cells in rats, and has a significant inhibitory effect on lipidized peroxidation of organs such as skin, heart and kidneys in rats.
Figure 4. The antioxidant effect of resveratrol The pharmacological function of resveratrol in suppressing or eliminating oxidizing free fundamentals has attracted wide attention from researchers and involves many physiological diseases closely related to human health, such as atherosclerosis, drug-based and viral hepatitis, acute or chronic stomach ulcers, allergic reactions, etc.
(4) combination of anti-inflammatory, antibacterial microorganisms and inflammatory responses is the cause of many skin diseases, such as Staphylococcus auspicyanin infection hair follicles, follicleitis.
redness and itching are common signs of foot, femoral and body palate.
combination of antimicrobial and anti-inflammatory treatments is an ideal treatment for alleviating this skin condition.
, the researchers further explored whether resveratrol is resistant to bacteria and fungi.
results of antibacterial experiments showed that resveratrol had a strong inhibitory effect on a variety of bacteria, such as Staphylococcus acobacteria, E. coli and E. coli.
, on the other hand, experimental anti-inflammatory studies have shown that resveratrol can achieve therapeutic effect by reducing plateplate adhesion and changing plateboard activity during the anti-inflammatory process.
, despite extensive laboratory and animal studies, there is little clinical evidence that resveratrol is an effective human therapy drug.
, the author summarizes the clinical data accumulated by resveratrol in the fields of tumor, neurological disease, cardiovascular disease, diabetes, fatty liver, obesity, and so on.
to choose these disease categories is that most of the clinical data on resveratrol are associated with them.
1. Clinical Effects of Cancer Resveratrol At a Glance The Excellent Nutritional Effects of Resveratrol Market Resveratrol have received wide attention from all parties.
market forecasts, the potential for resveratrol to be used in supplements is currently quite strong, especially for specific diseases.
dietary supplements are one of the most widely used areas of resveratrol, and the beverage industry is more receptive to resveratrol, especially functional beverages, than the food industry in new food and beverage products.
, consumer preference for natural products will also drive the widespread use of resveratrol in supplements.
according to incomplete statistics, global consumption of resveratrol grew at an average rate of 5.59 per cent.
Since 2015, the United States has accounted for 76.3 percent of new resveratrol-containing products worldwide, compared with 15.1 percent for Europe as a whole, and the vast majority of nutritional products containing resveratrol currently come from the United States.
U.S. is the largest consumer because of greater downstream application demand.
In the past two years, there have been nearly a thousand approved resveratrol drugs and health care products in the U.S. and Europe, with about 200 million users worldwide, and an average annual growth rate of 50 million people, with the global market for resveratrol at $49 million in 2017, continuing to soar at a compound annual growth rate of 8%.
According to the relevant forecasts, sales of resveratrol preparations will reach 500 million to 800 million U.S. dollars in the next 8 years, the expansion of the pharmaceutical and health care products market will further promote the growth of its raw material demand, resveratrol will form a huge industrial structure chain.
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