Analysis of Experimental Animal Model Market

Among the mammalian experimental animals, experimental mice are the most widely used

1.

In 1909, Clarence Cook Little in the laboratory of Professor William Ernest Castle of Harvard University obtained the first inbred mouse strain DBA with homozygous alleles and consistent genetic background through inbreeding.

The development of microbial control in mice in the 1940s can control the mouse strains from being infected by specific pathogens, and they are SPF-level specific pathogen-free animals

In 1966, scientists discovered spontaneously mutated nude mice with immunodeficiency phenotypes.

Since the 1970s, genetically engineered mice have entered the public eye

The emergence of targeted gene editing technology in this century has once again revolutionized the paradigm of life science research

2.
Development history of experimental mouse models in my country

The development of experimental animal mouse models in China started relatively late.
It was first started by Professor Qi Changqing in 1918 at the former Peking Central Epidemic Prevention Office
.

In 1946, Professor Tang Feifan introduced Swiss mice, which were later bred into Kunming mice that are widely used
.
In the 1950s, in order to prevent various infectious diseases, a large number of vaccines and vaccines were researched and produced.
China has successively established six biological product research institutes in Beijing, Shanghai, Wuhan, Changchun, Chengdu, and Lanzhou, and established relatively large-scale research institutes.
Large experimental animal breeding and breeding base
.

In 1982, the National Science and Technology Commission held the first National Laboratory Animal Science and Technology Work Conference.
In 1988, the "Regulations on the Management of Laboratory Animals" was issued, followed by the "Methods for the Quality Management of Laboratory Animals", "Measures for the Management of Laboratory Animal Licenses (Trial)" and other laws and regulations Also introduced one after another, mouse strain breeding, quality control and standardization construction are developing rapidly.
Experimental mouse model strains used in specific disease research are constantly being cultivated and introduced, and the number of use is increasing rapidly, and they are widely used in life science research and new drug development
.

Domestic and foreign market size

According to Frost & Sullivan statistics, the global animal model market (excluding animal model related services) has grown from 10.
8 billion U.
S.
dollars in 2015 to 14.
6 billion U.
S.
dollars in 2019, with a compound annual growth rate of 7.
8%
.
By 2024, the global animal model market is expected to grow to 22.
6 billion U.
S.
dollars, with a compound annual growth rate of 9.
2%
.

The animal model market in China is relatively in an early stage of development and rapid growth
.
According to Frost&Sullivan's calculations, in terms of total revenue, China's animal model market (excluding animal model-related services) has grown from US$200 million in 2015 to US$400 million in 2019, with a compound annual growth rate of 16.
9%
.
It is estimated that by 2024, the total animal model market in China will grow to US$1.
5 billion, with a compound annual growth rate of approximately 28.
1%
.

Rodent experimental animals are the most important category of experimental animal models.
Among the experimental rodent animal models, mouse models account for 85%.
The domestic product and service market is also growing rapidly.
The market size in 2019 is 28.
It is estimated that the market size will reach 8.
4 billion yuan by 2024, with a compound annual growth rate of approximately 24.
4%; by 2030, the overall market size of domestic experimental mouse products and services will reach 23.
6 billion yuan
.

The sales customers of domestic laboratory mouse products and services are mainly divided into scientific research customers and industrial customers
.
Scientific research customers mainly include scientific research institutions and tertiary hospitals.
In 2019, the market size was 1.
59 billion yuan, with a market share of 56.
0%
.
Industrial customers mainly include innovative pharmaceutical companies and CRO R&D companies.
The market size in 2019 was 1.
25 billion yuan, accounting for 44.
0% of the market
.
If split according to the disease field, the market is mainly concentrated in tumor immunity, metabolic diseases, and neurological diseases.
The market size is 1.
87 billion yuan, 420 million yuan and 320 million yuan, and the market share is 66.
0%, 14.
8%, 11.
2%
.

Industry competitive landscape

There are not many major domestic and foreign companies involved in animal models.
Among them, foreign companies have studied this aspect earlier, and the company's establishment time is generally earlier than domestic ones
.

Major players at home and abroad

1.
Experimental mice

According to Frost&Sullivan statistics, in the Chinese laboratory mouse product and service market in 2019, Charles River’s subsidiary in China, Vitality, has a revenue of 220 million yuan and a market share of 7.
7%, ranking first, with major business types For the sale of finished mice
.
In 2019, Jicui Yaokang's business revenue was approximately RMB 190 million, with a market share of 6.
7%, ranking second
.

2.
Finished mice

In the field of finished mouse sales, the domestic market size in 2019 was 1.
6 billion yuan, and the business revenue of Weitong Lihua was 220 million yuan, occupying 13.
7% of the market share, ranking first
.
In 2019, the revenue scale of Jicui Yaokang's commercial mouse model business was 95.
27 million yuan, with a market share of 6.
0%.
In the field of customized mouse model services, the domestic market size in 2019 was 430 million yuan; four heads Enterprises occupy approximately 30.
0% of the market share
.

3.
Customized breeding service market

In the custom breeding service market, the domestic market size in 2019 was 600 million yuan; three head mouse companies accounted for about 22.
9% of the market share
.
Among them, the revenue scale of this business of Nanmo Biology in 2019 was 61 million yuan, and the market accounted for 10.
1%, including breeding and breeding business, ranking first; Jicui Yaokang ranked second
.

4.
Non-CMC preclinical drug research and development technical services

The current domestic non-CMC preclinical drug R&D technology service market accounts for a small share of the overall CRO market, and the market size in 2019 was RMB 87 million
.
Among them, in 2019, Biocytometer's revenue from this business was RMB 34 million, with a market share of 38.
6%, ranking first
.

to sum up

Laboratory animals are the cornerstone of the development of modern life science research and play the role of human substitutes
.
The research and development of innovative drugs has become a hot spot for investment worldwide.
The number of clinical trials of innovative drugs at various stages is showing a rapid growth trend.
As an indispensable experimental animal model for drug research and development, it has a broad market space
.

Reference: Prospectus of Jicui Yaokang