Analysis of F2-Isoprostanes by Gas Chromatography-Mass Spectrometry/Negative Ion Chemical Ionization
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Last Update: 2020-12-24
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Source: Internet
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Author: User
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Numerous methods have been developed to assess oxidative stress/injury in vivo in humans, which include products of oxidation of lipids, proteins, and
DNA
. However, it has long been recognized that most methods are unreliable because they measure products that are not specific products of free radical-induced oxidation, because the method is not specific for the oxidation product being measured, or because the method is too invasive for use in humans (
1
). Thus, it has long been recognized that there has been a need for a reliable method to assess oxidative stress status in vivo in humans.
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