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Hyperbaric oxygen refers to the treatment of breathing 100% pure oxygen at increased atmospheric pressure.
confirmed that human tissue in hyperbaric oxygen therapy significantly increased oxygenation, can be used to treat a variety of inflammation, including UC, and has good safety.
previous trials, the researchers confirmed that in addition to steroid use intravenously, the use of hyperbaric oxygen therapy significantly improved clinical response and remission rates in UC patients hospitalized for acute seizures.
the rate of progression to inflix monotherapy or colonectomy decreased significantly during hospitalization.
study is intended to explore this further.
recruited UC patients hospitalized for relapses of acute illness (Mayo score 6-12) to be included in the study.
, all patients received three days of hyperbaric oxygen therapy (90 minutes) at 2.4 atmospheres, in addition to steroid hormones given intravenously.
who had a therapeutic response on the third day (Mayo score reduction of 2 points and rectal bleeding score of 1 point) were randomly assigned to the hyperbaric oxygen therapy group for 5 and 3 days.
follow-up follow-up with all patients and perform statistical analysis.
results showed that in 20 hyperbaric oxygen patients, the response on the third day was 55% (n s 11/20), the number of stools, rectal bleeding and a significant decrease in CRP (P .lt;0.01).
a significant decrease in disease activity compared to 3 days of hyperbaric oxygen (P - 0.03), but only three patients (15%) required inflixi monoantigen or colonectomy.
, those who did not respond on the third day were less likely to need to be hospitalized again or have a colonectomy within 3 months (0% VS. 66%, P s 0.002).
hypobaric oxygen appears to be effective in induced remission in UC patients hospitalized for acute episodes of the disease, and the rate of re-hospitalization or colonectomy is low for three months, the researchers concluded.
best clinical response after 5 days of hyperbaric oxygen therapy.
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