Analysis of the negative effects of modern biogene engineering on human beings.

Biotechnology Channel News: Modern biotechnology is based on genetic engineering as the center of the transformation of biological features or access to biological products technology.
genetic engineering plays an increasingly important role in solving a series of major problems, such as human health, food shortage and environmental protection, is there any potential danger in the transformation of life genetic material in nature? It is generally believed that once a gene is modified, it may cause a series of unknown structure and function changes in the organism, and the effects of GM operation on the organism will be passed on in different ways, leading to the following problems.
(1) After the introduction of gene therapy, will it affect other important regulatory genes and even activate the primary cancer gene?(2) The wide application of genetically modified technology, will there be vector-mediated exogenetic gene lateral transfer, recombination of new strains, leading to the emergence of new pathogenic microorganisms difficult to eliminate?(3) Will the spread of GENETIC crops cause ecological disaster? Does genetically modified crops have new characteristics, which enhance their competitiveness to survive and become invasive organisms? Will herbicide-resistant genes pass from GENETIC crops to weeds through interbreeding between near-source species to produce super weeds? Or is the conversion of GM crops themselves into uncontrollable weeds that disrupt the ecological balance?(4) Whether disease-resistant and insect-resistant proteins produced in genetically modified crops with insect resistance will make diseases and insects resistant, making pests and diseases more difficult to control.
(5) Will the large amount of GM food that humans eat affect the health of humans and their descendants when GM products enter the food chain?Many scholars also believe that the vitality of genetically modified organisms is not as strong as people think, many crops pollen transmission distance is limited, such as corn 50 meters outside the planting area is difficult to see pollen.
other pollen has a limited survival time, such as the undergraduate plant pollen, in the normal environment can only survive 1-2h, to maintain fertilization capacity for a shorter time.
many plants are white pollinators, pollen is not easy to spread.
from the current field test results of genetically modified plants such as rice, corn, cotton, potatoes, flax and asparagus, genetically modified plants are no better than non-GMO plants in terms of growth potential and wintering capacity.
that most genetically modified plants have not increased their competitiveness, so they generally do not evolve into farm weeds.
the presence of plant virus heterogeneity recombination in the natural world to produce new viruses, which can change the scope of the virus's host.
so far, anti-viral genetically modified plants have not been found in field trials with viral iso-packaging, but long-term and large-scale applications will occur and further tests are needed to confirm.
genetic engineering technology to make plants resistant to insects, reduce the use of chemical pesticides, can avoid environmental pollution and residual pesticides on the human body.
, genetically modified insect-resistant plants may still have negative effects on the environment.
First, the cultivation of genetically modified insect-resistant plants may cause pest host transfer;
many beneficial organisms in natural conditions feed on pests, and the cultivation of genetically modified plants will reduce the number of pests, which will undoubtedly threaten the survival of some beneficial organisms that feed on pests.
although there is no direct evidence to date that anti-worm genes in genetically modified insect-resistant plants can poison predators of pests, this issue should be given high priority.
food safety is an important aspect of the safety evaluation of genetically modified plants.
1993, the International Organization for Economic Cooperation and Development proposed the principle of substantive equality in food safety evaluation.
If the products produced by genetically modified plants are substantially equivalent to traditional products, they can be considered safe, and if the products produced by genetically modified plants do not have substantial equivalents with traditional products, a strict safety evaluation should be carried out.
in conducting substantive equivalent evaluations, both toxic substances and allergens need to be taken into account, and it is important to ensure that the transferred exogenous genes or gene products are not toxic to humans and animals.
the safety of PTA insecticidal gene corn as feed or food, the safety of PTA protein in human and animal should be studied.
there is a large number of experimental data to prove that PTA protein is only toxic to a few target insects, safe for humans and animals.
There are many allergens under natural conditions, plants with allergen genes cannot be approved for commercial production, such as the U.S. someone in Brazil nut allergen 2S clear protein gene into soybeans, although soybean sulfur amino acids increased, also not approved for commercial production.
addition, there may be potential safety problems with marker genes in GENETIC crops, which can now be removed through gene deletion techniques by co-converting plants that can obtain unmarked genes.
.