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    Home > Active Ingredient News > Drugs Articles > Analysis on the inspection method and testing instrument of compound ointment tube

    Analysis on the inspection method and testing instrument of compound ointment tube

    • Last Update: 2019-11-12
    • Source: Internet
    • Author: User
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    The compound ointment tube is mainly used to hold ointment, whose quality is directly related to the quality of drugs At present, the common materials of composite medical ointment tubes are polyethylene / aluminum / polyethylene three-layer structure According to the new version of YBB standard, the test items of composite medical ointment tubes mainly include pressure strength test, inner and inner peel strength test, tensile strength test, thermal strength test, sealing test, barrier performance test (water vapor transmission and oxygen transmission), etc Multiple test indicators In order to facilitate the ointment and packaging enterprises to better understand the requirements of ybb00252005 for quality inspection, Jinan Languang Electromechanical Technology Co., Ltd combines the actual inspection experience of "Languang packaging safety inspection center" and the introduction of corresponding testing instruments as follows: 1 Pressure strength test of ointment tube 1 Test purpose : because the composite hose is made of composite membrane through the process of hot pressing and sealing If the process is not stable, it is easy to have the problem of strength dropping and leakage 2 Test method: take the sample, tighten the pipe cap, torque 30n.cm-90n.cm, add compressed air from the end of the pipe, air pressure is 0.2MPa, put it in the water, pressurize for 30s continuously, no fracture is allowed, and there shall be no bubble at the weld 3 Testing instrument: use njy-20 torque meter of Labthink Languang to tighten the tube cap of the ointment tube The tightening force shall not be less than 30n.cm After that, insert the chuck of lssd-01 leakage and sealing strength tester into the end of the ointment tube and place it in a special container (filled with water), then inject 200 kPa of air according to the standard, and detect the leakage within 30 seconds 2、 Detection of peel strength of inner layer and secondary inner layer of ointment tube 1 Test purpose: since the inner layer and aluminum layer are combined by bonding method, detection of peel strength of inner layer and secondary inner layer is an important parameter to determine composite state, so this inspection is required 2 Test method : test the sample according to the requirements of ybb000102003 standard, and note that the longitudinal and transverse peel strength shall not be less than 5N / 15mm (note that it must be the average value of the peel strength of the inner layer and the sub inner layer, rather than the large value of Zui) 3 Testing instrument: The XLW series intelligent electronic tensile testing machine can be used for inspection The sample is taken to be 15mm wide, pre peeled for 50mm, and then clamped between the upper and lower clamps of the intelligent electronic tensile testing machine The test speed is set to 300 mm / min, the test is started, and the test results are tested 3、 Tensile strength test of ointment tube 1 Test purpose: this index is an important index for judging the mechanical properties of materials 2 Test method: According to ybb00112003 standard, the longitudinal and transverse tensile strength shall be tested respectively, and the strength shall not be less than 16MPa As the material is composite, it is enough to record the load when the first layer (separator) material breaks 3 Test instrument: XLW series intelligent electronic tensile testing machine is used for inspection Take the pipes of the same batch number, after sampling, install the samples between the upper and lower clamps of the tensile machine, set the test speed to 100 mm / min, and test the load when the first layer of material (separator) breaks 4、 Heat sealing strength of pipe body and tail 1 Test purpose: judge the welding strength when the pipe is made of film 2 Test method: test according to ybb0012203 standard It is required that the heat sealing strength of the pipe body shall not be less than 70N / 15mm and that of the pipe tail shall not be less than 20n / 15mm 3 Test instrument: cut the sample evenly along the width direction for 15mm wide test, place both ends of the sample on the fixture of XLW series intelligent electronic tensile testing machine, set the test speed to 100mm / min, and record the test results 5、 Detection of barrier performance of ointment tube 1 Test purpose: barrier performance is an important performance index considering barrier performance of ointment tube material, which plays a key role in the control of permeability, anti rancidity, anti discoloration, anti hardening and anti oil-water separation of hose tube 2 Test method: the water vapor transmission shall be tested in accordance with ybb00092003 During the test, the heat seal shall face the side with low humidity, and the water vapor transmission shall not be more than 0.5g/m2.24h The oxygen transmission shall be tested in accordance with ybb00082003 During the test, the heat cover shall face the side with low pressure, and the oxygen transmission shall not be more than 0.5cm3/m2.24h.0.1mpa 3 Test instrument: The moisture permeability tester based on Labthink blue light's cup test principle and vac-v series differential pressure gas permeameter are respectively used for testing The instrument is a full-automatic and high-precision test, and the test efficiency is greatly improved Labthink is committed to helping customers to deal with packaging problems and help the quality and safety of packaging related industries through the improvement of packaging testing technology and the development of testing instruments The above information is specially arranged by Jinan Languang mechanical and Electrical Technology Co., Ltd in order to help the quality control of pharmaceutical composite ointment tube manufacturing and use enterprises At the same time, our company has a professional laboratory to carry out the inspection of all the above projects, hoping to exchange more problems with colleagues in the industry For more information, please call Jinan Languang or visit the company's website.
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