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    Analysis technology of imidazole and thiazole drug residues-extraction method

    • Last Update: 2021-10-10
    • Source: Internet
    • Author: User
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    18.


    There is almost no literature on the analysis of thiamidazole residues in animal-derived matrices.


    18.


    (1) Extraction method

    1) Liquid liquid extraction (LLE)

    Levamisole can be extracted with organic reagents such as acetonitrile , ethyl acetate , n-hexane -isoamyl alcohol, chloroform , and hydrochloride is commonly used, and the extraction efficiency is higher under alkaline conditions


    Crooks et al.


    Xu Jing et al.


    Baere et al.


    2) Ultrasonic-assisted extraction (UAE)

    UAE uses the cavitation effect of ultrasonic waves to increase the penetration of the solvent, increase the dissolution rate and the number of dissolution of the drug, thereby increasing the diffusion of material components, shortening the extraction time, and accelerating the extraction process


    3) Electromembrane extraction (electromembrane extraction)

    In recent years, the hollow fiber membrane extraction technology, as a sample pretreatment method, has been widely used in the fields of environmental analysis, drug analysis, and food and beverage testing


     

     

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