echemi logo
  • Product
  • Supplier
  • Inquiry
    Home > Biochemistry News > Biotechnology News > Anesthesia may affect the spread of tau protein in the brain and promote Alzheimer's disease

    Anesthesia may affect the spread of tau protein in the brain and promote Alzheimer's disease

    • Last Update: 2021-08-12
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit

    During the development and development of Alzheimer's disease, a protein called tau accumulates and diffuses in the brain

    Scientists pointed out that inflammation plays an important role in Alzheimer's disease, and microglia (immune cells in the brain) are thought to be involved in this process because it produces a type of interleukin-6.

    In the current research, the team has developed a new method to measure tau levels, called nanobeam sensor technology

    The team conducted experiments on mice and cells and found that sevoflurane causes tau to leave neurons and enter microglia, which stimulates the cells to produce interleukin-6, which in turn leads to inflammation and cognitive impairment

    "These data indicate the spread of anesthesia-related tau protein and its consequences," said Zhongcong Xie, senior author, MD, and director of the DACCPM Geriatric Anesthesia Research Unit

    Sevoflurane did not increase the release of lactate dehydrogenase in neurons, which is a molecule similar in size and weight to tau protein

    Another inhalation anesthetic called desflurane does not have the same effect as sevoflurane

    # # #

    This article is an English version of an article which is originally in the Chinese language on and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to with relevant evidence.