Animal live experiments have confirmed that the new crown vaccine nasal drip can play an immune effect.

To conduct the nasal inoculation experiment, a team at the University of Washington School of Medicine designed a candidate vaccine that encodes the new coronavirus prickly protein, which binds the host cells to the infection process.
researchers injected the vaccine into bioengineered mice with human subjects corresponding to the protein.
, after vaccination, no infectious virus was found in the lungs of mice exposed to the new coronavirus, but a small amount of viral RNA was indeed detected.
, no viral RNA was detected in mice vaccinated in the nasal cavity, combined with other evidence that nasal vaccination was fully immune.
At the same time, a team at the First Affiliated Hospital of Guangzhou Medical University conducted experiments on rhesus monkeys using another vaccine that encodes the new coronavirus prickly protein, and the researchers found that nasal inoculation, like traditional injections, could help prevent viral infections.
at the end of the experiment, 9 bits of rhesus monkeys that received different doses of injections or nasal immunity were sampled and tested negative for viral nucleic acids.
, high-volume viruses were detected at different locations in unvaccinated monkeys.
researchers say the discovery of nasal inoculation methods can make vaccination easier by allowing people to drip into the vaccine themselves, while the nasal immunity approach is expected to reduce the potential immune problems caused by the adenovirus vector itself and achieve better immune results.
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