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Recently, published in the Journal of nutrition, an animal study from South Korean scientists found that citrus aurantium Linn é (CA) can help obese mice lose weight and reduce cholesterol Mice were fed with 60% kcal high fat food (HFD) for four weeks to induce obesity They were divided into two groups (n = 5) and fed with HFD or HFD + Ca (100mg / kg / day) for 8 weeks The control group was given normal diet (nd) for 12 weeks, and the weight of mice was measured twice a week, and the contents of high-density lipoprotein (HDL), low-density lipoprotein (LDL) and total cholesterol in blood were measured This study reported that there were significant differences in body weight (50.31 ± 0.84g and 40.91 ± 0.91g, respectively) between HFD group and HFD + Ca group after 12 weeks This suggests that CA can regulate the weight of mice fed high fructose corn syrup, the researchers said It was also found that the weight of fat tissue in CA treated obese mice decreased by 35% (P = 0.0143) CA may directly inhibit fat production by white fat cells and regulate heat production by brown fat cells, both of which are attractive anti obesity strategies, the researchers said The results showed that Ca (1000 μ g / ml) could inhibit lipid accumulation and reduce mRNA expression to participate in the formation of white fat This study also indicated that CA can regulate the thermogenesis of brown fat cells According to the researchers, brown fat uses energy specifically to reduce weight gain by producing heat The results show that CA can significantly reduce body weight in obese mice, which suggests that Ca may be a potential intervention against obesity