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Primary hyperparathyroidism (PHPT) is a common endocrine disorder associated with increased risk and increased mortality from fractures, cardiovascular disease, kidney disease, and cancer
Blood vessel
Recently, a research article was published in Annals of Internal Medicine, an authoritative journal of internal medicine, to investigate the effect of PTX on mortality (primary endpoint) and key morbidity (secondary endpoint) in mild PHPT
This prospective randomized controlled trial (ClinicalTrials.
After 10 years, 15 patients had died (8 in the PTX group and 7 in the OBS group)
cardiovascular events
CONCLUSIONS: Parathyroidectomy does not appear to reduce morbidity or mortality in patients with mild PHPT
Parathyroidectomy does not appear to reduce morbidity or mortality in patients with mild PHPT
Original source:
Mikkel Pretorius, et al.